Date published: 2026-7-29

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3-[(2,3-Dihydro-1H-inden-5-yloxy)methyl]piperidinehydrochloride

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Molecular Weight:
267.8
Molecular Formula:
C15H22ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Z-VAD(OMe)-FMK is an irreversible and cell permeable broad-spectrum Caspase Inhibitor displaying an IC50 of 5.8 nM in HepG2 cells. Z-VAD(OMe)-FMK may act to inhibit caspase-1 and caspase-3. Z-VAD(OMe)-FMK also been shown to inhibit Fas-mediated apoptosis in Jurkat T cells and apoptosis in THP.1 cells induced by diverse stimuli (including cycloheximide, thapsigargin, etoposide and staurosporine). Furthermore, anti-CD95-induced hepatocyte apoptosis was prevented in a concentration-dependent manner by inhibitor Z-VAD-FMK (IC50 = 1.5 nM). Additionally, Z-VAD(OMe)-FMK has been shown that pretreatment of MDA-MB-231 and HL-60 cells with Z-VAD(OMe)-FMK also inhibits apoptosis.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-[(2,3-Dihydro-1H-inden-5-yloxy)methyl]piperidinehydrochloride, 500 mg

sc-312032
500 mg
$259.00