Anticorps 26S Proteasome p54 (439): sc-65746
- L'Anticorps 26S Proteasome p54 (439) est un monoclonal de souris IgG1 κ, cité dans 3 publications, fourni en 200 µg/ml
- élevé contre le protéasome 26S purifié à partir d'embryons d'origine Drosophila melanogaster.
- recommandé pour la détection de p54 subunit of the 19S regulatory base complex of the 26S Proteasome d'origine d par WB, IP et IF
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire 26S Proteasome p54 (439). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
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The 26S proteasome is a large complex involved in the intracellular degradation of proteins in eukaryotes. Ubiquitination by E3 ubiquitin ligases targets proteins for degradation by this complex. The 26S proteasome plays an important role in the regulation of many biological processes. It is composed of over 30 different subunits and contains at least two copies of each subunit. Assembly of this large complex is ATP-dependent. Due to its size, it is fairly unstable and often disassociates into subcomplexes (including a 20S core and two 19S regulatory complexes). The 26S proteasome p54 (also known as Rpn10 in yeast and S5a in human) is one of the four non-ATPase base subunits of the 19S regulatory complex. The 26S proteasome p54 is a multiubiquitin binding subunit responsible for the peptidase activity of the 26S proteasome. In the presence of zinc this subunit dissociates from the 19S complex causing peptidase activity to be lost. Once dissociated, the 26S Proteasome p54 interacts with non-proteasomal proteins HSP 82, Smt3, and UBC9.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps 26S Proteasome p54 (439) | sc-65746 | 200 µg/ml | $316.00 |