SPRR2B activators belong to a class of chemical compounds designed to interact with and modulate the activity of the SPRR2B protein. SPRR2B, or Small Proline-Rich Protein 2B, is a member of the small proline-rich protein family, which is characterized by their high proline content and their involvement in various cellular processes such as differentiation, wound healing, and barrier function. SPRR2B, specifically, is primarily expressed in epithelial tissues, including the skin, oral mucosa, and esophagus, where it is believed to play crucial roles in maintaining tissue integrity and providing protection against environmental stressors. The designation activators suggests that these compounds engage with SPRR2B to modulate its activity, potentially leading to downstream effects on cellular physiology and tissue homeostasis.
Research into SPRR2B activators involves elucidating the molecular mechanisms underlying their interaction with the SPRR2B protein and how this interaction influences cellular processes, particularly in epithelial tissues. Understanding the pharmacological properties of these compounds is vital for deciphering how they impact SPRR2B activity and potentially affect epithelial barrier function, wound healing, and other physiological processes. By unraveling the biological functions and regulatory mechanisms of SPRR2B, researchers aim to deepen our understanding of epithelial biology and may uncover novel insights into the molecular pathways underlying tissue integrity and repair. Continued investigation into SPRR2B activators holds promise for advancing our knowledge of epithelial physiology and may provide insights into new strategies for manipulating tissue homeostasis in experimental contexts.
| Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Métabolite de la vitamine A, l'acide tout-trans rétinoïque influence la différenciation des cellules de la peau et pourrait réguler SPRR2B dans le cadre de la réponse de la peau à la signalisation rétinoïde. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
La forme active de la vitamine D, le calcitriol, module la croissance et la différenciation des cellules de la peau, influençant potentiellement l'expression de SPRR2B dans les cellules épidermiques. | ||||||
Tazarotene | 118292-40-3 | sc-220193 | 10 mg | $103.00 | ||
Le tazarotène peut affecter la prolifération et la différenciation des cellules de la peau, en augmentant probablement la régulation de SPRR2B. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
L'acide salicylique, un acide bêta-hydroxylé utilisé dans le traitement de l'acné et du psoriasis, pourrait influencer l'expression de SPRR2B par ses effets sur le renouvellement des cellules de la peau. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Forme de vitamine B3, le nicotinamide a des propriétés anti-inflammatoires et peut moduler l'expression de SPRR2B dans le contexte de la réparation et du maintien de la barrière cutanée. | ||||||
Hyaluronic acid | 9004-61-9 | sc-337865 | 10 mg | $204.00 | ||
L'acide hyaluronique pourrait influencer l'expression de SPRR2B en améliorant la fonction et la réparation de la barrière cutanée. | ||||||
Glycerol | 56-81-5 | sc-29095A sc-29095 | 100 ml 1 L | $55.00 $150.00 | 12 | |
Le glycérol attire l'humidité dans la peau, affectant potentiellement l'expression de SPRR2B dans le processus d'hydratation et de réparation de la peau. | ||||||