Date published: 2025-11-24

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SPRR2B Activateurs

SPRR2B activators belong to a class of chemical compounds designed to interact with and modulate the activity of the SPRR2B protein. SPRR2B, or Small Proline-Rich Protein 2B, is a member of the small proline-rich protein family, which is characterized by their high proline content and their involvement in various cellular processes such as differentiation, wound healing, and barrier function. SPRR2B, specifically, is primarily expressed in epithelial tissues, including the skin, oral mucosa, and esophagus, where it is believed to play crucial roles in maintaining tissue integrity and providing protection against environmental stressors. The designation activators suggests that these compounds engage with SPRR2B to modulate its activity, potentially leading to downstream effects on cellular physiology and tissue homeostasis.

Research into SPRR2B activators involves elucidating the molecular mechanisms underlying their interaction with the SPRR2B protein and how this interaction influences cellular processes, particularly in epithelial tissues. Understanding the pharmacological properties of these compounds is vital for deciphering how they impact SPRR2B activity and potentially affect epithelial barrier function, wound healing, and other physiological processes. By unraveling the biological functions and regulatory mechanisms of SPRR2B, researchers aim to deepen our understanding of epithelial biology and may uncover novel insights into the molecular pathways underlying tissue integrity and repair. Continued investigation into SPRR2B activators holds promise for advancing our knowledge of epithelial physiology and may provide insights into new strategies for manipulating tissue homeostasis in experimental contexts.

Nom du produitCAS #Ref. CatalogueQuantitéPrix HTCITATIONS Classement

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Métabolite de la vitamine A, l'acide tout-trans rétinoïque influence la différenciation des cellules de la peau et pourrait réguler SPRR2B dans le cadre de la réponse de la peau à la signalisation rétinoïde.

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$325.00
$632.00
$1428.00
$2450.00
$400.00
32
(2)

La forme active de la vitamine D, le calcitriol, module la croissance et la différenciation des cellules de la peau, influençant potentiellement l'expression de SPRR2B dans les cellules épidermiques.

Tazarotene

118292-40-3sc-220193
10 mg
$103.00
(0)

Le tazarotène peut affecter la prolifération et la différenciation des cellules de la peau, en augmentant probablement la régulation de SPRR2B.

Salicylic acid

69-72-7sc-203374
sc-203374A
sc-203374B
100 g
500 g
1 kg
$46.00
$92.00
$117.00
3
(1)

L'acide salicylique, un acide bêta-hydroxylé utilisé dans le traitement de l'acné et du psoriasis, pourrait influencer l'expression de SPRR2B par ses effets sur le renouvellement des cellules de la peau.

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$43.00
$65.00
$200.00
$815.00
6
(1)

Forme de vitamine B3, le nicotinamide a des propriétés anti-inflammatoires et peut moduler l'expression de SPRR2B dans le contexte de la réparation et du maintien de la barrière cutanée.

Hyaluronic acid

9004-61-9sc-337865
10 mg
$204.00
(0)

L'acide hyaluronique pourrait influencer l'expression de SPRR2B en améliorant la fonction et la réparation de la barrière cutanée.

Glycerol

56-81-5sc-29095A
sc-29095
100 ml
1 L
$55.00
$150.00
12
(5)

Le glycérol attire l'humidité dans la peau, affectant potentiellement l'expression de SPRR2B dans le processus d'hydratation et de réparation de la peau.