Pma1p Activateurs
The chemicals listed here are considered indirect modulators of Pma1p. They do not activate Pma1p directly but may influence its activity by affecting cellular energy status, ion homeostasis, or membrane potential - all crucial factors for Pma1p function. Compounds like Vanadate, Bafilomycin A1, and Concanamycin A, known for their inhibitory effects on various ATPases, could impact cellular ion gradients and ATP availability, thereby indirectly influencing Pma1p activity. Mitochondrial inhibitors such as Oligomycin, FCCP, DCCD, Azide, Antimycin A, and DNP can alter the cellular energy balance. Since Pma1p activity is energy-dependent, these changes could indirectly affect its function.
Ionophores like Valinomycin, Nigericin, and Monensin alter ion gradients across membranes. By disrupting these gradients, they could indirectly influence the activity of Pma1p, which is pivotal in maintaining ion homeostasis and membrane potential in yeast cells. It's important to recognize that the influence of these chemicals on Pma1p is indirect and speculative, based on their known actions on related cellular processes. The actual impact on Pma1p would depend on several factors, including the specific cellular context, the concentration of the chemicals, and the presence of other interacting proteins and pathways. These chemicals should be used with caution and in a controlled experimental setup to understand their specific effects on Pma1p and related cellular functions.
VOIR ÉGALEMENT...
| Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
|---|---|---|---|---|---|---|
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
Le FCCP découple la phosphorylation oxydative mitochondriale, affectant potentiellement l'équilibre énergétique cellulaire et la fonction de la Pma1p. | ||||||
Valinomycin | 2001-95-8 | sc-200991 | 25 mg | $163.00 | 3 | |
La valinomycine, un ionophore de potassium, pourrait affecter les gradients ioniques, ce qui pourrait avoir un impact sur le rôle de Pma1p dans le maintien du potentiel membranaire. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
La monensine, un ionophore Na+/H+, pourrait affecter l'homéostasie ionique, influençant ainsi potentiellement l'activité de Pma1p. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $42.00 $152.00 $385.00 $845.00 $88.00 | 8 | |
L'azide inhibe la cytochrome c oxydase dans la chaîne de transport d'électrons, ce qui pourrait indirectement affecter Pma1p en modifiant le statut énergétique. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
L'antimycine A, un inhibiteur du transport d'électrons mitochondrial, peut avoir un impact indirect sur Pma1p par le biais de changements dans l'énergétique cellulaire. | ||||||
2,4-Dinitrophenol, wetted | 51-28-5 | sc-238345 | 250 mg | $58.00 | 2 | |
Le DNP découple la phosphorylation oxydative, affectant potentiellement l'activité de la Pma1p en modifiant la synthèse de l'ATP et la disponibilité de l'énergie. | ||||||
Concanamycin A | 80890-47-7 | sc-202111 sc-202111A sc-202111B sc-202111C | 50 µg 200 µg 1 mg 5 mg | $65.00 $162.00 $650.00 $2550.00 | 109 | |
La concanamycine A, un autre inhibiteur de la V-ATPase, pourrait affecter indirectement la Pma1p en influençant les processus d'acidification intracellulaire. | ||||||