LOC644838 Activators refers to a group of chemical entities that, if the locus were known to be associated with a protein, would be defined by their ability to enhance the activity of said protein encoded by the gene at the LOC644838 genomic locus. The LOC prefix typically denotes a 'locus,' a specific location on a chromosome that may represent a gene whose products and functions are not fully characterized. As of the latest scientific data available to me, there is no recognized gene or protein associated with the designation LOC644838, so the notion of LOC644838 Activators is entirely speculative and does not correspond to a recognized category in chemistry or biology. However, assuming the existence of such a protein, activators would be compounds that bind to it in a manner that increases its natural activity. This could involve a direct interaction with the protein's active site to enhance its function or an allosteric effect where the binding of the activator at a site distinct from the active site induces a conformational change that results in increased activity.
In exploring the concept of LOC644838 Activators further in a theoretical context, the identification and study of such compounds would involve a multifaceted approach. Biochemists would initiate by developing assays to detect the activity of the LOC644838 protein, which would allow for the screening of potential activator compounds. These assays might include colorimetric tests for enzymatic activity, fluorescence-based assays for binding or activity, or electrophysiological measurements if the protein were part of an ion channel or receptor system. Following the initial discovery phase, detailed kinetic studies would be performed to understand the interaction between the activators and the protein, revealing the potency, efficacy, and mechanism of activation. Structural biologists might utilize techniques such as X-ray crystallography or cryo-electron microscopy to elucidate the complex between the protein and activator molecules, providing a detailed view of the interaction at an atomic level. Complementary to these experimental techniques, computational chemists would employ in silico modeling and simulations to predict how these activators interact with the protein and to explore the effects of these interactions on the protein's dynamics and conformation. Through an integrative approach combining empirical evidence with computational predictions, scientists would aim to thoroughly characterize the chemical nature and mode of action of LOC644838 Activators within this theoretical framework.
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Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Cet inhibiteur de l'ADN méthyltransférase pourrait entraîner une déméthylation des promoteurs de gènes, ce qui pourrait accroître l'expression de l'ARNlc. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
En tant qu'inhibiteur d'HDAC, la trichostatine A peut modifier la structure de la chromatine, ce qui peut entraîner une augmentation de la transcription des ARNlc. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
L'acide rétinoïque peut moduler l'expression des gènes par l'intermédiaire de ses récepteurs nucléaires, ce qui pourrait affecter les niveaux d'ARNlc. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Le lithium influence la voie de signalisation Wnt et pourrait avoir un impact sur l'expression des gènes, y compris les lincRNA. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
En tant qu'hormone, le β-estradiol peut réguler l'expression des gènes par l'intermédiaire des récepteurs d'œstrogènes, affectant potentiellement l'expression des ARNlc. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Cet inhibiteur d'HDAC peut entraîner un remodelage de la chromatine et influencer l'expression des ARNlc. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Inhibiteur du facteur de transcription Sp1 susceptible d'altérer la transcription des gènes et des lincRNA régulés par Sp1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
La rapamycine inhibe la signalisation mTOR, ce qui pourrait entraîner des changements dans les modèles d'expression génétique, y compris les lincRNA. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
Affecte l'activité des facteurs de transcription et l'expression des gènes, et peut influencer de manière non spécifique l'expression des ARNlc. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
En modulant la voie PI3K/Akt, ces inhibiteurs pourraient modifier les profils d'expression génétique, y compris celui des lincRNA. |