G Protein-Coupled Receptor 20 (GPR20) is a protein in humans encoded by the GPR20 gene. This protein belongs to the family of G protein-coupled receptors (GPCRs), which are involved in transmitting signals across cell membranes. GPCRs are a large and diverse group of proteins that play crucial roles in many different biological processes and are targets for a large number of drugs.GPCRs function by binding to specific molecules outside the cell (ligands), which causes a conformational change in the receptor and initiates a series of events inside the cell. These intracellular events, often involving the activation of G proteins, lead to a cellular response.
Many GPCRs have unknown ligands and are referred to as orphan receptors until their ligand is discovered. GPR20 falls into this category.In terms of disease associations there is limited information about GPR20. Some studies suggest potential links between variations in the GPR20 gene and certain phenotypic traits or disease susceptibilities, but these associations are not yet well established and require further investigation.In summary, GPR20 is a G protein-coupled receptor with an as-yet unknown specific ligand and function. Its potential involvement in disease and its role within the broader context of GPCR signaling are areas of ongoing research. This makes GPR20 an interesting target for further study, as understanding its function could provide new insights into cellular signaling and potential targets.
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| Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
|---|---|---|---|---|---|---|
Pilocarpine | 92-13-7 | sc-479256 | 100 mg | $255.00 | 1 | |
La pilocarpine, un agoniste des récepteurs muscariniques, peut moduler la signalisation des RCPG, en affectant indirectement le GPR20. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
L'adénosine active les récepteurs de l'adénosine, qui font partie de la famille des GPCR, influençant potentiellement les voies liées au GPR20. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
La dopamine, par son action sur les récepteurs de la dopamine, peut influencer indirectement la signalisation GPR20. | ||||||
Oxytocin acetate salt | 50-56-6 | sc-279938 sc-279938A sc-279938B sc-279938C sc-279938D sc-279938E | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $60.00 $180.00 $337.00 $663.00 $969.00 $1836.00 | 4 | |
L'ocytocine, un autre ligand du GPCR, pourrait avoir des effets indirects sur la fonction du GPR20. | ||||||
3-(2-Aminoethyl)-1H-indol-5-ol | 50-67-9 | sc-298707 | 1 g | $530.00 | 3 | |
La sérotonine, par son action sur les récepteurs de la sérotonine (GPCR), peut influencer indirectement le GPR20. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
L'histamine, agissant sur les récepteurs de l'histamine (qui font partie des RCPG), pourrait moduler indirectement l'activité du GPR20. | ||||||