The chemical class of C9orf5 Inhibitors represents a diverse and sophisticated collection of compounds, each playing a role in the modulation of the protein encoded by the C9orf5 gene. This class underscores a strategic approach in targeting various biochemical pathways and cellular processes to influence protein function, especially in scenarios where direct inhibitors are not clearly defined. The assortment of mechanisms utilized by these compounds highlights the intricate nature of protein regulation and the potential for modulating protein activity through indirect influence on related cellular pathways.
Central to this class are compounds like Melatonin and Theophylline. Melatonin, known for its role in regulating circadian rhythms, also modulates oxidative stress, suggesting a possible impact on C9orf5 activity.
Flavonoids such as Rutin and Luteolin bring another dimension to this class. Rutin's ability to modulate vascular function and inflammation, along with Luteolin's impact on inflammation and cellular signaling, illustrate how natural compounds found in plants can play a role in influencing protein activities like those of C9orf5. These compounds demonstrate the intersection between natural plant-derived substances and their implications in modulating protein function.
Ellagic Acid and Astaxanthin, both found in natural sources, emphasize the significance of dietary components in influencing cellular physiology. Ellagic Acid, found in fruits, and Astaxanthin, a carotenoid, show how compounds that affect oxidative stress and inflammation can have potential implications for proteins involved in similar pathways.
Nicotinamide, a form of vitamin B3, and Alpha-Linolenic Acid, an omega-3 fatty acid, further expand the scope of this class. Nicotinamide's role in modulating cellular metabolism and DNA repair, along with Alpha-Linolenic Acid's impact on inflammation and lipid metabolism, highlight the intricate ways in which different compounds can influence protein functions.
Carnosine and Silymarin represent the potential of compounds to affect protein functions through modulation of protein glycation, oxidative stress, and liver function. These compounds illustrate the importance of targeting specific biochemical pathways for influencing protein activity.
Ginkgo Biloba Extract, known for its effect on blood circulation and oxidative stress, underscores the role of traditional herbal supplements in potentially influencing protein activities like C9orf5.
In summary, the "C9orf5 Inhibitors" class represents a comprehensive and multi-faceted approach to influencing protein activity. This class not only sheds light on the complex regulation of proteins like C9orf5 but also underscores the broader implications of such modulation in cellular physiology. The diversity of mechanisms within this class reflects the intricate nature of cellular functioning and the ongoing efforts to understand and manipulate protein activity for various purposes. As research continues to advance, this class of inhibitors offers valuable insights into protein regulation, opening new avenues for intervention and advancing our understanding of cellular and molecular biology.
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| Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Un métabolite qui agit comme un inhibiteur des phosphoinositides 3-kinases (PI3K), affectant potentiellement les protéines impliquées dans les voies de signalisation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Un inhibiteur chimique des PI3K, qui peut modifier les voies de signalisation en aval dans lesquelles une protéine comme C9orf51 peut être impliquée. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Un immunosuppresseur qui inhibe mTOR et peut affecter les voies de synthèse des protéines qui peuvent impliquer C9orf51. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Un inhibiteur de l'histone désacétylase qui peut modifier les schémas d'expression des gènes, affectant potentiellement les protéines régulées par des mécanismes épigénétiques. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Composé qui s'incorpore à l'ADN et à l'ARN et agit comme inhibiteur de l'ADN méthyltransférase, modifiant éventuellement l'expression des protéines. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Un inhibiteur du protéasome qui peut empêcher la dégradation des protéines, affectant potentiellement les niveaux de C9orf51. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibiteur de la p38 MAP kinase qui peut modifier l'activation des protéines impliquées dans les voies de réponse au stress et à l'inflammation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibiteur de la c-Jun N-terminal kinase (JNK), qui peut affecter les voies de signalisation et les interactions protéiques. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibiteur de la MEK qui peut empêcher l'activation de la MAPK/ERK, affectant éventuellement les protéines régulées par cette voie. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Un composé qui peut moduler de multiples voies de signalisation et peut influencer l'activité de diverses protéines. | ||||||