Zacopride hydrochloride is a highly potent SR-3 antagonist (Ki = 0.38 nM) and SR-4 agonist (Ki = 373 nM). Zacopride hydrochloride is anti-emetic and anxiolytic following systemic administration in vivo.
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Estado de Materia
Soluble to 100 mM in Water and to 100 mM in DMSO, to 100 mM in PBS, and to 75 mM in Ethanol
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