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TR4 Antibody (95-P) is a mouse monoclonal IgG1 antibody that detects TR4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). TR4, an orphan receptor belonging to the steroid/thyroid hormone receptor superfamily, plays a crucial role in various biological processes, including neurogenesis and germ cell development, by forming heterodimers with TR2. This interaction enhances the functional diversity of the receptor complex, allowing for precise regulation of gene expression in response to developmental cues. TR4 is also involved in the regulation of genes such as the erythropoietin gene and the muscle-specific aldolase A gene, highlighting TR4′s importance in cellular differentiation and growth. Furthermore, TR4′s expression can be influenced by factors such as p53 and ionizing radiation, suggesting TR4′s potential role in linking stress responses to steroid receptor signaling pathways. Anti-TR4 antibody (95-P) is an essential tool for researchers investigating the intricate mechanisms of receptor signaling and their implications in development and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TR4 Antibody (95-P) | sc-130409 | 100 µg/ml | $339.00 |