TR4 Antibody (D-5): sc-365895
- TR4 Antibody (D-5) is a mouse monoclonal IgG1 κ TR4 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 41-76 of TR4 of mouse origin
- TR4 Antibody (D-5) is recommended for detection of TR4 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TR4 Antibody (D-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TR4 Antibody (D-5) for WB applications. These reagents are now offered in bundles with TR4 Antibody (D-5) (see ordering information below).
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TR4 Antibody (D-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects TR4 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TR4 (D-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TR4, an orphan receptor belonging to the steroid/thyroid hormone receptor superfamily, plays a crucial role in regulating gene expression related to growth, differentiation, and development. TR4 interacts with TR2, forming heterodimers that are implicated in neurogenesis and germ cell development, highlighting these interactions′ importance in cellular processes. TR4 regulates genes such as erythropoietin and muscle-specific aldolase A, which are essential for proper cellular function and response to physiological demands. Understanding TR4 dynamics and interactions is vital for elucidating its role in various biological pathways and potential implications in disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TR4 Antibody (D-5) References:
- Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily. | Chang, C., et al. 1994. Proc Natl Acad Sci U S A. 91: 6040-4. PMID: 8016112
- Suppression of the human erythropoietin gene expression by the TR2 orphan receptor, a member of the steroid receptor superfamily. | Lee, HJ., et al. 1996. J Biol Chem. 271: 10405-12. PMID: 8626614
- p53 is a mediator for radiation-repressed human TR2 orphan receptor expression in MCF-7 cells, a new pathway from tumor suppressor to member of the steroid receptor superfamily. | Lin, DL. and Chang, C. 1996. J Biol Chem. 271: 14649-52. PMID: 8663350
- Identification of the human aldolase A gene as the first induced target for the TR2 orphan receptor, a member of the steroid hormone receptor superfamily. | Chang, C., et al. 1997. Biochem Biophys Res Commun. 235: 205-11. PMID: 9196064
- A bidirectional regulation between the TR2/TR4 orphan receptors (TR2/TR4) and the ciliary neurotrophic factor (CNTF) signaling pathway. | Young, WJ., et al. 1998. J Biol Chem. 273: 20877-85. PMID: 9694834
- A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4. | Lee, CH., et al. 1998. J Biol Chem. 273: 25209-15. PMID: 9737983
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TR4 Antibody (D-5) | sc-365895 | 200 µg/ml | $322.00 | |||
TR4 Antibody (D-5): m-IgG Fc BP-HRP Bundle | sc-529501 | 200 µg Ab; 10 µg BP | $361.00 | |||
TR4 Antibody (D-5): m-IgGκ BP-HRP Bundle | sc-522409 | 200 µg Ab, 40 µg BP | $361.00 | |||
TR4 Antibody (D-5): m-IgG1 BP-HRP Bundle | sc-543546 | 200 µg Ab; 20 µg BP | $361.00 | |||
TR4 Antibody (D-5) AC | sc-365895 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TR4 Antibody (D-5) HRP | sc-365895 HRP | 200 µg/ml | $322.00 | |||
TR4 Antibody (D-5) FITC | sc-365895 FITC | 200 µg/ml | $336.00 | |||
TR4 Antibody (D-5) PE | sc-365895 PE | 200 µg/ml | $349.00 | |||
TR4 Antibody (D-5) Alexa Fluor® 488 | sc-365895 AF488 | 200 µg/ml | $364.00 | |||
TR4 Antibody (D-5) Alexa Fluor® 546 | sc-365895 AF546 | 200 µg/ml | $364.00 | |||
TR4 Antibody (D-5) Alexa Fluor® 594 | sc-365895 AF594 | 200 µg/ml | $364.00 | |||
TR4 Antibody (D-5) Alexa Fluor® 647 | sc-365895 AF647 | 200 µg/ml | $364.00 | |||
TR4 Antibody (D-5) Alexa Fluor® 680 | sc-365895 AF680 | 200 µg/ml | $364.00 | |||
TR4 Antibody (D-5) Alexa Fluor® 790 | sc-365895 AF790 | 200 µg/ml | $364.00 |