Date published: 2026-7-28

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Tosufloxacin tosylate (CAS 115964-29-9)

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Alternate Names:
7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid tosylate; A-64730
Application:
Tosufloxacin tosylate is an antibacterial agent that inhibits bacterial DNA gyrase inhibitor
CAS Number:
115964-29-9
Purity:
≥98%
Molecular Weight:
576.55
Molecular Formula:
C19H15F3N4O3•C7H8O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tosufloxacin tosylate is a fluoroquinolone antibacterial agent. Tosufloxacin tosylate is also a bacterial Topo (DNA gyrase, topoisomerase)) inhibitor. Tosufloxacin tosylate is effective against Gram-positive and Gram-negative aerobic bacteria, anaerobic bacteria and Chlamydia trachomatis.


Tosufloxacin tosylate (CAS 115964-29-9) References

  1. [In vitro bactericidal effect of temafloxacin and tosufloxacin against streptococci].  |  Aubert, G., et al. 1991. Pathol Biol (Paris). 39: 1002-5. PMID: 1666667
  2. Comparison of moxifloxacin and levofloxacin in an epithelial disorder model using cultured rabbit corneal epithelial cell sheets.  |  Miyake, T., et al. 2012. Graefes Arch Clin Exp Ophthalmol. 250: 1035-41. PMID: 22282216
  3. [Mn2+-cTMAB-sensitized fluorescent microscopic determination of tosufloxacin tosylate based on a self-ordered ring].  |  Deng, FY., et al. 2014. Guang Pu Xue Yu Guang Pu Fen Xi. 34: 445-9. PMID: 24822418
  4. Tosufloxacin deposits in compromised corneas.  |  Kim, YD., et al. 2014. Optom Vis Sci. 91: e241-4. PMID: 25036547
  5. Probing the interaction of cefodizime with human serum albumin using multi-spectroscopic and molecular docking techniques.  |  Hu, T. and Liu, Y. 2015. J Pharm Biomed Anal. 107: 325-32. PMID: 25637820
  6. Enhanced Neuronal Survival and Neurite Outgrowth Triggered by Novel Small Organic Compounds Mimicking the LewisX Glycan.  |  Theis, T., et al. 2018. Mol Neurobiol. 55: 8203-8215. PMID: 29520715
  7. Comprehensive screening of antimicrobials to control phytoplasma diseases using an in vitro plant-phytoplasma co-culture system.  |  Tanno, K., et al. 2018. Microbiology (Reading). 164: 1048-1058. PMID: 29952745
  8. Simultaneous Determination of 15 Sulfonate Ester Impurities in Phentolamine Mesylate, Amlodipine Besylate, and Tosufloxacin Tosylate by LC-APCI-MS/MS.  |  Jin, B., et al. 2019. J Anal Methods Chem. 2019: 4059765. PMID: 31687249
  9. Effect of xanthan gum-based food thickeners on the dissolution profile of fluoroquinolones oral formulations.  |  Takahashi, N., et al. 2020. J Pharm Health Care Sci. 6: 25. PMID: 33292643
  10. Dissolution Profiles of Immediate Release Products of Various Drugs in Biorelevant Bicarbonate Buffer: Comparison with Compendial Phosphate Buffer.  |  Okamoto, N., et al. 2024. Pharm Res. 41: 959-966. PMID: 38653942

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tosufloxacin tosylate, 250 mg

sc-204920
250 mg
$98.00

Tosufloxacin tosylate, 1 g

sc-204920A
1 g
$294.00