TMEM192 Antibody (F-12): sc-518207
- TMEM192 Antibody (F-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 190-212 of TMEM192 of human origin
- recommended for detection of TMEM192 of human origin by WB, IP, IF and ELISA
- Anti-TMEM192 Antibody (F-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP is the preferred secondary detection reagent for TMEM192 Antibody (F-12) for WB applications. This reagent is now offered in a bundle with TMEM192 Antibody (F-12) (see ordering information below).
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SEE ALSO...
TMEM192 Antibody (F-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects TMEM192 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-TMEM192 antibody (F-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TMEM192 is a 271 amino acid protein encoded by a gene located on human chromosome 4, which harbors nearly 900 genes and represents about 6% of the human genome. TMEM192 is primarily localized in the endoplasmic reticulum, where TMEM192 plays a crucial role in cellular processes such as protein folding and quality control. This localization is significant because the endoplasmic reticulum is essential for the synthesis and maturation of secretory and membrane proteins, and any dysfunction in this organelle can lead to various diseases, including neurodegenerative disorders. Additionally, chromosome 4 contains genes associated with several genetic conditions, such as Huntington′s disease and achondroplasia, highlighting the importance of studying TMEM192 in understanding cellular mechanisms and potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TMEM192 Antibody (F-12) References:
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. | Hillier, LW., et al. 2005. Nature. 434: 724-31. PMID: 15815621
- Selective neuronal degeneration in Huntington's disease. | Cowan, CM. and Raymond, LA. 2006. Curr Top Dev Biol. 75: 25-71. PMID: 16984809
- Syndromic craniosynostosis: from history to hydrogen bonds. | Cunningham, ML., et al. 2007. Orthod Craniofac Res. 10: 67-81. PMID: 17552943
- Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. | Ruiz-Perez, VL., et al. 2007. Development. 134: 2903-12. PMID: 17660199
- Growth hormone analysis and treatment in Ellis-van Creveld syndrome. | Versteegh, FG., et al. 2007. Am J Med Genet A. 143A: 2113-21. PMID: 17702014
- Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle. | Chandler, RJ., et al. 2007. BMC Med Genet. 8: 64. PMID: 17937813
- Muenke syndrome (FGFR3-related craniosynostosis): expansion of the phenotype and review of the literature. | Doherty, ES., et al. 2007. Am J Med Genet A. 143A: 3204-15. PMID: 18000976
- Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice. | Stack, EC., et al. 2007. J Neurosci. 27: 12908-15. PMID: 18032664
- Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias. | de Frutos, CA., et al. 2007. Dev Cell. 13: 872-83. PMID: 18061568
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMEM192 Antibody (F-12) | sc-518207 | 200 µg/ml | $322.00 | |||
TMEM192 Antibody (F-12): m-IgG1 BP-HRP Bundle | sc-551170 | 200 µg Ab; 20 µg BP | $361.00 | |||
TMEM192 Antibody (F-12) AC | sc-518207 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TMEM192 Antibody (F-12) HRP | sc-518207 HRP | 200 µg/ml | $322.00 | |||
TMEM192 Antibody (F-12) FITC | sc-518207 FITC | 200 µg/ml | $336.00 | |||
TMEM192 Antibody (F-12) PE | sc-518207 PE | 200 µg/ml | $349.00 | |||
TMEM192 Antibody (F-12) Alexa Fluor® 488 | sc-518207 AF488 | 200 µg/ml | $364.00 | |||
TMEM192 Antibody (F-12) Alexa Fluor® 546 | sc-518207 AF546 | 200 µg/ml | $364.00 | |||
TMEM192 Antibody (F-12) Alexa Fluor® 594 | sc-518207 AF594 | 200 µg/ml | $364.00 | |||
TMEM192 Antibody (F-12) Alexa Fluor® 647 | sc-518207 AF647 | 200 µg/ml | $364.00 | |||
TMEM192 Antibody (F-12) Alexa Fluor® 680 | sc-518207 AF680 | 200 µg/ml | $364.00 | |||
TMEM192 Antibody (F-12) Alexa Fluor® 790 | sc-518207 AF790 | 200 µg/ml | $364.00 |