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Sulbactam sodium salt (CAS 69388-84-7)

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Alternate Names:
Betamaze
Application:
Sulbactam sodium salt is a LACTB (β-lactamase) inhibitor that has similar characteristics as ampicillin
CAS Number:
69388-84-7
Molecular Weight:
255.22
Molecular Formula:
C8H10NO5S•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sulbactam sodium salt is a compound that acts by inhibiting the action of certain enzymes produced by bacteria, which are for their survival and multiplication. This inhibition mechanism makes it particularly effective in combating bacterial resistance to other agents. Sulbactam is combined with other substances to enhance its effectiveness against a wide range of bacterial infections.


Sulbactam sodium salt (CAS 69388-84-7) References

  1. An efficient method for the synthesis of sulbactam pivoxil.  |  Changov, LS., et al. 2000. Farmaco. 55: 134-5. PMID: 10782385
  2. Investigation of oxacillin-hydrolyzing beta-lactamase in borderline methicillin-resistant clinical isolates of Staphylococcus aureus.  |  Gál, Z., et al. 2001. Chemotherapy. 47: 233-8. PMID: 11399858
  3. Physicochemical compatibility between ketoprofen lysine salt injections (Artrosilene Fiale) and pharmaceutical products frequently used for combined therapy.  |  Anacardio, R., et al. 2002. Boll Chim Farm. 141: 122-7. PMID: 12135160
  4. A new fractional wavelet approach for the simultaneous determination of ampicillin sodium and sulbactam sodium in a binary mixture.  |  Dinç, E. and Baleanu, D. 2006. Spectrochim Acta A Mol Biomol Spectrosc. 63: 631-8. PMID: 16024281
  5. A fatal case of suspected anaphylaxis with cefoperazone and sulbactam: LC-MS analysis.  |  Tsujikawa, K., et al. 2008. J Forensic Sci. 53: 226-31. PMID: 18279263
  6. Effect of beta-lactamase inhibitors on the activities of various beta-lactam agents against anaerobic bacteria.  |  Wexler, HM., et al. 1991. Antimicrob Agents Chemother. 35: 1219-24. PMID: 1929265
  7. Liquid chromatography/tandem mass spectrometry assay for the simultaneous determination of cefoperazone and sulbactam in plasma and its application to a pharmacokinetic study.  |  Zhou, Y., et al. 2010. J Chromatogr B Analyt Technol Biomed Life Sci. 878: 3119-24. PMID: 20971044
  8. Stability of sulbactam/ampicillin in diluents for parenteral administration.  |  Mushinsky, RF., et al. 1986. Rev Infect Dis. 8 Suppl 5: S523-7. PMID: 3026000
  9. A case report of rash induced by cefoperazone sodium and sulbactam sodium plus metronidazole sodium chloride combined with morphine hydrochloride.  |  Huang, J., et al. 2020. Ann Palliat Med. 9: 4377-4383. PMID: 33302688
  10. In vitro and in vivo activity of meropenem+avibactam against MBL-producing carbapenem-resistant Klebsiella pneumoniae.  |  Li, X., et al. 2023. Expert Rev Anti Infect Ther. 21: 91-98. PMID: 36433637
  11. Pharmacokinetics of sulbactam in humans.  |  Foulds, G., et al. 1983. Antimicrob Agents Chemother. 23: 692-9. PMID: 6307133
  12. Comparative pharmacokinetics of ampicillin-sulbactam combination in calves and sheep.  |  Montesissa, C., et al. 1994. J Vet Pharmacol Ther. 17: 359-64. PMID: 7853460
  13. Stability of aztreonam and ampicillin sodium-sulbactam sodium in 0.9% sodium chloride injection.  |  Belliveau, PP., et al. 1994. Am J Hosp Pharm. 51: 901-4. PMID: 8017440
  14. Quantifying Permeation of Small Charged Molecules across Channels: Electrophysiology in Small Volumes  |  Jiajun Wang, Lorraine Benier, and Mathias Winterhalter*, et al. 2018. ACS Omega. 3: 17481–17486.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sulbactam sodium salt, 500 mg

sc-394497
500 mg
$213.00