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SOCS-3 Antibody (SO1) - Western Blotting - Image 388022
SOCS-3 抗体 (SO1): sc-51699. MC3T3-E1 全细胞裂解液 (A) 和小鼠 PBL (B), 小鼠脾脏 (C) 和大鼠 PBL (D) 组织提取物中 SOCS-3 表达的 Western 印迹分析.
SOCS-3 抗体 (SO1): sc-51699. MC3T3-E1 全细胞裂解液 (A) 和小鼠 PBL (B), 小鼠脾脏 (C) 和大鼠 PBL (D) 组织提取物中 SOCS-3 表达的 Western 印迹分析.

SOCS-3 抗体 (SO1): sc-51699

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说明书
  • SOCS-3 抗体 SO1 是小鼠单克隆 IgG2b, 在18篇文献中引用，提供 100 µg/ml
  • 针对纯化的human全长天然SOC3蛋白
  • 推荐用于 mouse, rat 和 human 来源的SOCS-3 WB, IP 和 ELISA检测
  • 2b BP-HRP">m-IgG2b BP-HRP是SOCS-3 Antibody (SO1) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与SOCS-3 Antibody (SO1) 打包提供（请参阅下面的订购信息）。
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関連項目

额外SOCS抗体，包括SOCS-1, SOCS-3, SOCS-4, SOCS-5, SOCS-6和SOCS-7

SOCS-3抗体（SO1）是一种IgG2b小鼠单克隆SOCS-3抗体，可通过WB、IP和ELISA检测来自小鼠、大鼠和人类的SOCS-3。SOCS-3抗体（SO1）可以是非偶联的抗SOCS-3抗体形式。SOCS（细胞因子信号抑制因子）基因家族由一组蛋白质组成，可以抑制细胞因子信号转导。SOCS家族蛋白质包含一个中央SH2结构域和一个称为"SOCS box"的羧基末端区域。已知SOCS-1（也称为SSI-1和JAB）、SOCS-2（也称为SSI-2和CIS2）和SOCS-3（也称为SSI-3和CIS3）基因受IL-6和其他细胞因子的上调调控。SOCS-4、SOCS-5、SOCS-6和SOCS-7是通过其与SOCS box的序列同源性而被识别出来的。CIS（细胞因子诱导的SH2含量蛋白）也是SOCS家族的成员。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SOCS-3 抗体 (SO1) 参考文献:

  1. SOCS-3诱导肌细胞分化。  |  Spangenburg, EE. 2005. J Biol Chem. 280: 10749-58. PMID: 15653674
  2. Barrett腺癌发生中SOCS-3和SOCS-1的甲基化。  |  Tischoff, I., et al. 2007. Gut. 56: 1047-53. PMID: 17376806
  3. SOCS-3蛋白在瘦素抵抗和肥胖中的作用。  |  Lubis, AR., et al. 2008. Acta Med Indones. 40: 89-95. PMID: 18560028
  4. 星形胶质细胞中SOCS-1和SOCS-3的表达和功能意义。  |  Qin, H., et al. 2008. J Immunol. 181: 3167-76. PMID: 18713987
  5. 在 Bcr-Abl 诱导的肿瘤发生过程中需要 SOCS-1 和 SOCS-3 磷酸化。  |  Qiu, X., et al. 2012. Neoplasia. 14: 547-58. PMID: 22787435
  6. 心脏猝死患者心肌中SOCS-1和SOCS-3的表达。  |  Chen, L., et al. 2010. World J Emerg Med. 1: 99-103. PMID: 25214949
  7. SOCS-1和SOCS-3的低表达是胃癌患者不良预后的指标。  |  Li, G., et al. 2015. J Cancer Res Clin Oncol. 141: 443-52. PMID: 25261987
  8. SOCS-3和SOCS-4的体外意义以及与伤口愈合的潜在机理联系  |  Feng, Y., et al. 2017. Sci Rep. 7: 6715. PMID: 28751715
  9. 组织水平上抑制细胞因子信号传导-3（SOCS-3）在真菌病中的水平。  |  Nada, HR., et al. 2023. Arch Dermatol Res. 315: 165-171. PMID: 35226171
  10. 丙戊酸对结肠癌中SOCS-1、SOCS-2、SOCS-3、SOCS-5、SOCS-6和SOCS-7基因表达和细胞生长抑制的影响。  |  Sanaei, M., et al. 2022. Gastroenterol Hepatol Bed Bench. 15: 39-44. PMID: 35611249

订购信息

产品名称产品编号规格价格数量收藏夹

SOCS-3 抗体 (SO1)

sc-51699
100 µg/ml
$322.00

SOCS-3 (SO1): m-IgG2b BP-HRP 套装

sc-548433
100 µg Ab; 10 µg BP
$361.00

Can we use this antibody for IF assay? If yes, what concentration do you suggest? If no, do you have SOCS3 antibodies for IF?

Asked by: as11
Thank you for your question. We have not yet tested this antibody for IF, or immunofluorescent staining, so this application is not recommended at this time. Unfortunately, we do not have any alternative antibodies against SOCS-3 that are recommended for IF at this time.
Answered by: Technical Support
Date published: 2017-07-27

For Western Blot, is it recommended to use denatured or non-denatured conditions with SOCS-3 (SO1): sc-51699 antibody?

Asked by: Dr Ninau Qelp
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by janin from good results in WBstrong and specific band in western blot wit mice liver lysates, dilution 1:1000
Date published: 2018-09-05
Rated 5 out of 5 by yanli from 细胞免疫荧光刚试用了细胞免疫荧光，抗体说明书中没有表明可以用于此实验，但在293T细胞中试用结果很好，主要染色胞质。
Date published: 2017-10-26
Rated 5 out of 5 by nichaoying from This antibody worked greatThis antibody worked great. I strongly recommend this antibody for detection of SOCS-3.
Date published: 2017-10-23
Rated 4 out of 5 by M__T_ from Worked in WB using mouse/human cellsWorked in WB using mouse/human cells.
Date published: 2015-09-15
Rated 5 out of 5 by SM from WB: human and mouse cell lysatesWB: human and mouse cell lysates. -SCBT Publication Review
Date published: 2015-05-18
Rated 5 out of 5 by JL from Published western blot data using human bloodPublished western blot data using human blood samples. -SCBT Publication Review
Date published: 2015-04-03
Rated 5 out of 5 by FL from Nice band in WB using HeLa cell lysatesNice band in WB using HeLa cell lysates. -SCBT QC
Date published: 2015-01-21
Rated 4 out of 5 by SH from Positive western blot results in HeLaPositive western blot results in HeLa, IFN -treated HeLa, IL-6-treated HeLa and human PBL whole cell lysates. -SCBT QC
Date published: 2015-01-11
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SOCS-3抗体 (SO1) is rated 4.8 out of 5 by 9.
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