Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
SMRT Antibody (1212) is a high quality monoclonal SMRT antibody (also designated Nuclear Receptor Corepressor 2 antibody, SMRT antibody, Thyroid- Retinoic-Acid-Receptor-Associated Corepressor antibody, T3 Receptor-Associating Factor antibody, CTG Repeat Protein 26 antibody, N-CoR2 antibody, TNRC14 antibody, TRAC antibody, Silencing Mediator Of Retinoic Acid And Thyroid Hormone Receptor antibody, SMRTE-Tau antibody, or TRAC1 antibody) suitable for the detection of the SMRT protein of human origin. SMRT Antibody (1212) is available as both the non-conjugated anti-SMRT antibody form, as well as multiple conjugated forms of anti-SMRT antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Retinoids are metabolites of vitamin A (retinol) and represent important signaling molecules during vertebrate development and tissue differentiation. Retinoic acid receptors (RARs) have a high affinity for all trans retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. Two cofactors that function to repress transcription, designated SMRT (silencing mediator for RARs and thyroid receptors (TR)) and N-CoR, associate with TR and RAR in their unliganded state and are released from them upon ligand binding. The carboxy termini of both proteins contain receptor interacting domains while their amino termini contain two repressor domains. SMRT is 1495 amino acids and contains an 8 amino acid sequence that is not present in SMRTe (SMRT-extended), which contains 2514 amino acids. SMRTe contains an N-terminal sequence spanning over 1,000 amino acids that is not present in SMRT, but that shows significant similarity with N-CoR. SMRTe expression is regulated during cell cycle progression, suggesting a role for SMRTe in the regulation of cycle-specific gene expression in diverse signaling pathways.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
What is the recommended starting dilution for Western blot for sc-32298: SMRT (1212) monoclonal antibody?
Preguntado por: Cweed
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol:
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn