PU.1/Spi1 Antibody (G-11): sc-390618
- PU.1/Spi1 Antibody (G-11) is a mouse monoclonal IgA κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 33-61 near the N-terminus of PU.1 of mouse origin
- recommended for detection of PU.1 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-390618 X, 200 µg/0.1 ml)
- See PU.1/Spi1 (C-3): sc-390405 for PU.1/Spi1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PU.1/Spi1 Antibody (G-11). This work is in progress.
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SEE ALSO...
PU.1 Antibody (G-11) is a mouse monoclonal IgA antibody that detects PU.1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PU.1 is a critical transcription factor belonging to the Ets family, playing a vital role in the regulation of gene expression during lymphoid development and immune response. PU.1 is primarily located in the nucleus of hematopoietic cells, where anti-PU.1 antibody (G-11) can detect specific DNA sequences bound to activate or repress target genes essential for B cell differentiation and function. PU.1′s nuclear localization orchestrates transcriptional programs necessary for the development of various immune cell types, including B cells and T cells, thereby influencing the overall immune system′s functionality. PU.1 interacts with other proteins such as Spi-B and Spi-C, which further modulate activity and contribute to the complex regulatory networks governing hematopoiesis. PU.1 (G-11) antibody serves as an invaluable tool for researchers studying immune cell development and function, providing insights into molecular mechanisms underlying immune responses and potential therapeutic targets for immune-related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PU.1/Spi1 Antibody (G-11) | sc-390618 | 200 µg/ml | $322.00 | |||
PU.1/Spi1 (G-11) Neutralizing Peptide | sc-390618 P | 100 µg/0.5 ml | $69.00 | |||
PU.1/Spi1 Antibody (G-11) X | sc-390618 X | 200 µg/0.1 ml | $322.00 |