Prostaglandin D2 methyl ester (CAS 49852-81-5)
Prostaglandin D2 methyl ester is a more lipid-soluble, cell-permeable prodrug form of prostaglandin D2 (PGD2). Studies have shown that it has a 5-10 fold lower affinity for PGD2 receptors than PGD2.
References
1. Hayaishi, O., et al., 1988. Sleep-wake regulation by prostaglandins D2 and E2. The Journal of biological chemistry. 263(29): 14593-6. PMID: 3049580
2. Onoe, H., et al., 1988. Prostaglandin D2, a cerebral sleep-inducing substance in monkeys. Proceedings of the National Academy of Sciences of the United States of America. 85(11): 4082-6. PMID: 3163802
3. Giles, H., et al., 1988. The biology and pharmacology of PGD2. Prostaglandins. 35(2): 277-300. PMID: 3283848
4. Suzuki, F., et al., 1987. Methyl ester of prostaglandin D2 as a delivery system of prostaglandin D2 into brain. Biochimica et biophysica acta. 917(2): 224-30. PMID: 3467795
5. Li, Jianjun., et al., 2003. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life sciences. 73(9): 1083-96. PMID: 12818718
6. Hirai, Hiroyuki., et al., 2003. Gene structure and functional properties of mouse CRTH2, a prostaglandin D2 receptor. Biochemical and biophysical research communications. 307(4): 797-802. PMID: 12878180
Descargar SDS (MSDS)
CERTIFICADO DE ANÁLISIS
Necesita Adobe Acrobat Reader para ver de forma fiable,
imprimir y comentar el documento de PDF