Date published: 2026-5-3

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Pidotimod (CAS 121808-62-6)

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Alternate Names:
(4R)-3-{[(2S)-5-oxopyrrolidin-2-yl]carbonyl}-1,3-thiazolidine-4-carboxylic acid; (R)-3-((S)-5-Oxoprolyl)-4-thiazolidinecarboxylic acid
Application:
Pidotimod is a synthetic dipeptide with immunological modulatory activity on both the adaptive and innate immune responses
CAS Number:
121808-62-6
Purity:
≥98%
Molecular Weight:
244.27
Molecular Formula:
C9H12N2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A biological response modifier that inhibits apoptosis induced by several agents, including genistein.


Pidotimod (CAS 121808-62-6) References

  1. Immune modulator pidotimod decreases the in vitro expression of CD30 in peripheral blood mononuclear cells of atopic asthmatic and normal children.  |  Gourgiotis, D., et al. 2004. J Asthma. 41: 285-7. PMID: 15260461
  2. Pidotimod: a reappraisal.  |  Riboldi, P., et al. 2009. Int J Immunopathol Pharmacol. 22: 255-62. PMID: 19505378
  3. Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level.  |  Giagulli, C., et al. 2009. Int Immunopharmacol. 9: 1366-73. PMID: 19712757
  4. The regulatory peptide pidotimod facilitates M2 macrophage polarization and its function.  |  Hu, S., et al. 2014. Amino Acids. 46: 1177-85. PMID: 24481486
  5. Pharmacokinetics of pidotimod in broiler chickens by UHPLC-MS/MS after oral and intravenous administration.  |  Zhang, R., et al. 2018. Biomed Chromatogr. 32: PMID: 29105801
  6. Pidotimod in the treatment of pediatric recurrent respiratory tract infection.  |  Li, X., et al. 2019. Pak J Med Sci. 35: 981-986. PMID: 31372128
  7. Pidotimod: a review of its pharmacological features and clinical effectiveness in respiratory tract infections.  |  Zhao, N., et al. 2019. Expert Rev Anti Infect Ther. 17: 803-818. PMID: 31603361
  8. Pidotimod enhanced the anti-growth effect of cisplatin on lung cancer in mice via promoting anti-tumor immune response.  |  Wu, T., et al. 2020. Biochem Biophys Res Commun. 528: 678-684. PMID: 32513535
  9. Pidotimod increases inflammation in wounded zebrafish embryos.  |  Ding, L., et al. 2022. Fish Shellfish Immunol. 120: 429-433. PMID: 34922016
  10. Immunomodulating activity of pidotimod.  |  Migliorati, G., et al. 1994. Arzneimittelforschung. 44: 1421-4. PMID: 7857335

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pidotimod, 1 g

sc-204846
1 g
$97.00

Pidotimod, 5 g

sc-204846A
5 g
$459.00

Could you tell me which amino acids form pidotimod?

Asked by: brunopizzul1972
Thank you for your question. Pidotimod is (4R)-3-{[(2S)-5-oxopyrrolidin-2-yl]carbonyl}-1,3-thiazolidine-4-carboxylic acid; (R)-3-((S)-5-Oxoprolyl)-4-thiazolidinecarboxylic acid.
Answered by: Tech Support Europe
Date published: 2024-10-08
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Rated 5 out of 5 by from Giagulli et alGiagulli et al. (PubMed ID 19712757) found that pidotimod, a synthetic capable of modulating immune cell functions, induced mucosal dendritic cell maturation and promoted the activation of the innate immune system. -SCBT Publication Review
Date published: 2015-01-09
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Pidotimod is rated 5.0 out of 5 by 1.
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