Date published: 2026-5-5

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Peramivir (CAS 330600-85-6)

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Alternate Names:
BCX 1812; RWJ 270201
CAS Number:
330600-85-6
Molecular Weight:
328.41
Molecular Formula:
C15H28N4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Peramivir is a compound that is often used in virology research, where it serves as a tool to study the mechanisms of viral replication and the inhibition of neuraminidase enzymes. Researchers utilize peramivir to investigate the life cycle of influenza viruses, as it binds to the active site of the neuraminidase protein, providing insights into the enzyme′s structure and function. This compound is also valuable in the study of viral pathogenesis and the identification of viral resistance patterns. In the context of enzyme kinetics, peramivir is used to examine the effects of neuraminidase inhibitors on enzymatic activity, including the determination of inhibition constants and the assessment of inhibitor binding. Additionally, peramivir′s interactions with neuraminidase can be analyzed through computational modeling and crystallography, contributing to a deeper understanding of antiviral strategies at the molecular level.


Peramivir (CAS 330600-85-6) References

  1. Peramivir (BCX-1812, RWJ-270201): potential new therapy for influenza.  |  Sidwell, RW. and Smee, DF. 2002. Expert Opin Investig Drugs. 11: 859-69. PMID: 12036429
  2. Peramivir: an intravenous neuraminidase inhibitor for the treatment of 2009 H1N1 influenza.  |  Mancuso, CE., et al. 2010. Ann Pharmacother. 44: 1240-9. PMID: 20516360
  3. Peramivir and its use in H1N1 influenza.  |  Castillo, R., et al. 2010. Drugs Today (Barc). 46: 399-408. PMID: 20571608
  4. Balancing societal needs and regulatory certainty: the case study of peramivir in Japan.  |  Tominaga, T., et al. 2013. Clin Pharmacol Ther. 93: 342-4. PMID: 23422872
  5. Safety and efficacy of peramivir for influenza treatment.  |  Hata, A., et al. 2014. Drug Des Devel Ther. 8: 2017-38. PMID: 25368514
  6. Peramivir (Rapivab): an IV neuraminidase inhibitor for treatment of influenza.  |  . 2015. Med Lett Drugs Ther. 57: 17-9. PMID: 25629811
  7. Peramivir: an intravenous neuraminidase inhibitor.  |  McLaughlin, MM., et al. 2015. Expert Opin Pharmacother. 16: 1889-900. PMID: 26153242
  8. Peramivir: A Novel Intravenous Neuraminidase Inhibitor for Treatment of Acute Influenza Infections.  |  Alame, MM., et al. 2016. Front Microbiol. 7: 450. PMID: 27065996
  9. Comparison of Efficacy of Intravenous Peramivir and Oral Oseltamivir for the Treatment of Influenza: Systematic Review and Meta-Analysis.  |  Lee, J., et al. 2017. Yonsei Med J. 58: 778-785. PMID: 28540991
  10. Peramivir conjugates as orally available agents against influenza H275Y mutant.  |  Wang, PC., et al. 2018. Eur J Med Chem. 145: 224-234. PMID: 29324342
  11. Peramivir for Influenza A and B Viral Infections: A Pharmacokinetic Case Series.  |  Cies, JJ., et al. 2019. Pharmacotherapy. 39: 1060-1065. PMID: 31514223
  12. Antiviral Treatments for Influenza.  |  Palomba, E., et al. 2021. Semin Respir Crit Care Med. 42: 859-872. PMID: 34918326
  13. Peramivir, an Anti-Influenza Virus Drug, Exhibits Potential Anti-Cytokine Storm Effects.  |  Zhang, CX., et al. 2022. Front Immunol. 13: 856327. PMID: 35296098

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Peramivir, 1 mg

sc-478569
1 mg
$317.00