Parvovirus Antibody (5G7): sc-52145

Parvovirus Antibody (5G7) is a mouse monoclonal IgG2a antibody that detects parvovirus with species reactivity specific to parvovirus through applications such as enzyme-linked immunosorbent assay (ELISA). Parvovirus is a member of the Parvoviridae family, characterized by its small size and linear, non-segmented single-stranded DNA genome, which averages around 5 kilobases. The viral capsid is composed of three structural proteins, VP1, VP2, and VP3, which assemble into a robust icosahedral structure that can withstand extreme conditions, including pH variations and temperatures up to 50°C. This resilience is crucial for viral survival and infectivity in various environments. Within the capsid, the single-stranded DNA genome is protected and features hairpin structures formed by approximately 115 nucleotide sequences at both the 5′ and 3′ ends, which play a significant role in viral life cycle. Parvoviruses, including the human variant B19, infect a wide range of mammalian species, with B19 being particularly notable for causing erythema infectiosum, a mild but contagious illness that primarily targets erythroid progenitor cells. The implications of parvovirus infections are especially concerning for pregnant women, as transmission to the fetus can potentially lead to severe complications. Anti-parvovirus antibody (5G7) serves as a valuable tool for researchers studying the biology and pathology of parvoviruses, enabling detection and quantification of viral proteins in various experimental settings.

The preferred Parvovirus antibody is Parvovirus Antibody (CPV1-2A1): sc-57961.