Date published: 2026-6-5

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Molinate (CAS 2212-67-1)

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Alternate Names:
S-ethyl azepane-1-carbothioate
CAS Number:
2212-67-1
Molecular Weight:
187.30
Molecular Formula:
C9H17NOS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Molinate is a preemergence herbicide belonging to the thiocarbamate group, specifically used for selectively controlling grass weeds in rice farming. Classified as an azepane with an (ethylsulfanyl)carbonyl group substitution on its nitrogen atom, it also serves as an antispermatogenic agent. Additionally, Molinate is identified as a monothiocarbamic ester.


Molinate (CAS 2212-67-1) References

  1. Acute exposure to molinate alters neuroendocrine control of ovulation in the rat.  |  Stoker, TE., et al. 2005. Toxicol Sci. 84: 38-48. PMID: 15601673
  2. Mode of action: reduction of testosterone availability--molinate-induced inhibition of spermatogenesis.  |  Kavlock, R. and Cummings, A. 2005. Crit Rev Toxicol. 35: 685-90. PMID: 16417035
  3. Effects of molinate on survival and development of Bombina orientalis (Boulenger) embryos.  |  Kang, HS., et al. 2009. Bull Environ Contam Toxicol. 82: 305-9. PMID: 19002362
  4. Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition.  |  Allen, EM., et al. 2010. Chem Res Toxicol. 23: 1843-50. PMID: 20954713
  5. Molinate quantification in environmental water by a glutathione-S-transferase based biosensor.  |  Oliveira, TI., et al. 2013. Talanta. 106: 249-54. PMID: 23598124
  6. Microbial degradation of the herbicide molinate by defined cultures and in the environment.  |  Nunes, OC., et al. 2013. Appl Microbiol Biotechnol. 97: 10275-91. PMID: 24193246
  7. Photocatalytic degradation of molinate in aqueous solutions.  |  Bizani, E., et al. 2014. Environ Sci Pollut Res Int. 21: 12294-304. PMID: 24928378
  8. Assessment of combined electro-nanoremediation of molinate contaminated soil.  |  Gomes, HI., et al. 2014. Sci Total Environ. 493: 178-84. PMID: 24946031
  9. Structure-guided engineering of molinate hydrolase for the degradation of thiocarbamate pesticides.  |  Leite, JP., et al. 2015. PLoS One. 10: e0123430. PMID: 25905461
  10. Molinate induces organ defects by promoting apoptosis, inflammation, and endoplasmic reticulum stress during the developmental stage of zebrafish.  |  Lee, H., et al. 2023. Sci Total Environ. 885: 163768. PMID: 37146827
  11. Testicular toxicity of molinate in the rat: metabolic activation via sulfoxidation.  |  Jewell, WT., et al. 1998. Toxicol Appl Pharmacol. 149: 159-66. PMID: 9571984
  12. Molinate: rodent reproductive toxicity and its relevance to humans--a review.  |  Wickramaratne, GA., et al. 1998. Regul Toxicol Pharmacol. 27: 112-8. PMID: 9671566
  13. The reproductive toxicity of molinate and metabolites to the male rat: effects on testosterone and sperm morphology.  |  Ellis, MK., et al. 1998. Toxicol Appl Pharmacol. 151: 22-32. PMID: 9705884

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Molinate, 100 mg

sc-250411
100 mg
$99.00