Molecular structure of Meropenem-d6, CAS Number: 1217976-95-8
Meropenem-d6 (CAS 1217976-95-8)
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Alternate Names:
Meropenem-d6 is known as a deuterium labelled derivative of Carbapenem.
Application:
Meropenem-d6 is a deuterium labelled carbapenem antibiotic intended for use as a standard for meropenem quantification.
CAS Number:
1217976-95-8
Molecular Weight:
389.50
Molecular Formula:
C17H19D6N3O5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Meropenem-d6 is a deuterium labelled carbapenem antibiotic. As a derivative of Carbapenem, it is ready for use as an internal standard for meropenem quantification via GC-MS or LC-MS. Meropenem-d6 is active against a variety of clinical isolates of Gram-positive and gram-negative bacteria in vitro. It may be formulated to use in the treatment of some bacterial infections.
Meropenem-d6 (CAS 1217976-95-8) References
- Cellular and molecular aspects of drugs of the future: meropenem. | Cottagnoud, P. 2002. Cell Mol Life Sci. 59: 1928-33. PMID: 12530523
- Pharmacokinetic and pharmacodynamic properties of meropenem. | Nicolau, DP. 2008. Clin Infect Dis. 47 Suppl 1: S32-40. PMID: 18713048
- Activity of meropenem, against gram-positive bacteria. | Kayser, FH., et al. 1989. J Antimicrob Chemother. 24 Suppl A: 101-12. PMID: 2808202
- Substantial Impact of Altered Pharmacokinetics in Critically Ill Patients on the Antibacterial Effects of Meropenem Evaluated via the Dynamic Hollow-Fiber Infection Model. | Bergen, PJ., et al. 2017. Antimicrob Agents Chemother. 61: PMID: 28264846
- A simple ultra-high-performance liquid chromatography-high resolution mass spectrometry assay for the simultaneous quantification of 15 antibiotics in plasma. | Lefeuvre, S., et al. 2017. J Chromatogr B Analyt Technol Biomed Life Sci. 1065-1066: 50-58. PMID: 28946125
- Impact of erythrocytes on bacterial growth and antimicrobial activity of selected antibiotics. | Nussbaumer-Pröll, AK., et al. 2019. Eur J Clin Microbiol Infect Dis. 38: 485-495. PMID: 30687870
- Augmented renal clearance is associated with inadequate antibiotic pharmacokinetic/pharmacodynamic target in Asian ICU population: a prospective observational study. | Wu, CC., et al. 2019. Infect Drug Resist. 12: 2531-2541. PMID: 31496765
- HILIC LC-MS/MS method for the quantification of cefepime, imipenem and meropenem. | Rehm, S. and Rentsch, KM. 2020. J Pharm Biomed Anal. 186: 113289. PMID: 32428767
- Non-invasive Drug Monitoring of β-Lactam Antibiotics Using Sweat Analysis-A Pilot Study. | Brasier, N., et al. 2020. Front Med (Lausanne). 7: 476. PMID: 32984371
- An isotope-dilution LC-MS/MS method for the simultaneous quantification of meropenem and its open-ring metabolite in serum. | Rakete, S., et al. 2021. J Pharm Biomed Anal. 197: 113944. PMID: 33588299
- Stability and Validation of a High-Throughput LC-MS/MS Method for the Quantification of Cefepime, Meropenem, and Piperacillin and Tazobactam in Serum. | Bjergum, MW., et al. 2021. J Appl Lab Med. 6: 1202-1212. PMID: 34086904
- UPLC-MS/MS Method for Simultaneous Determination of 14 Antimicrobials in Human Plasma and Cerebrospinal Fluid: Application to Therapeutic Drug Monitoring. | Sun, H., et al. 2022. J Anal Methods Chem. 2022: 7048605. PMID: 35036023
- Evaluation of cefuroxime concentration in the intrathecal and extrathecal compartments of the lumbar spine-an experimental study in pigs. | Kaspersen, AE., et al. 2023. Br J Pharmacol.. PMID: 36710378
- [Clinical pharmacology and indications of meropenem in severe pediatric infection]. | Honorato, J., et al. 1997. Enferm Infecc Microbiol Clin. 15 Suppl 1: 38-44. PMID: 9410068
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Meropenem-d6, 1 mg | sc-218695 | 1 mg | $376.00 | |||
Meropenem-d6, 10 mg | sc-218695A | 10 mg | $3079.00 |