MEK-2 Antibody (96): sc-136261
- MEK-2 Antibody (96) is a mouse monoclonal IgG2a, cited in 1 publications, provided at 50 µg/0.5 ml
- raised against amino acids 1-110 of MEK-2 of rat origin
- recommended for detection of MEK-2 of mouse, rat, human and canine origin by WB, IP and IF
- See MEK-2 (A-1): sc-13159 for MEK-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MEK-2 Antibody (96). This work is in progress.
MEK-2 Antibody (96) is a mouse monoclonal IgG2a antibody designed to target amino acids 1-110 of rat MEK-2, also known as MAP2K2 or MKK2. MEK-2 is a dual-specificity protein kinase integral to the MAPK/ERK signaling pathway, playing a crucial role in regulating cellular processes such as growth, differentiation, and survival. The structured kinase domain of MEK-2 enables phosphorylation of both threonine and tyrosine residues on downstream targets like ERK1/2, facilitating precise signal transduction. Understanding MEK-2′s structure is essential as this determines substrate specificity and interactions with regulatory proteins, ensuring accurate modulation of cellular responses. MEK-2′s conformation allows interaction with upstream activators and participation in feedback mechanisms that maintain cellular homeostasis. MEK-2 (96) monoclonal antibody exhibits broad species reactivity, recognizing MEK-2 from mouse, rat, human, and canine origins, and is ideal for applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). By targeting a conserved epitope within the N-terminal region, anti-MEK-2 antibody (96) provides reliable detection and quantification across various experimental models, enhancing research versatility and robustness. The high affinity and specificity of MEK-2 (96) antibody make this an indispensable tool for investigating the MAPK/ERK pathway, which is frequently implicated in cancer and other diseases. Whether exploring fundamental cellular mechanisms or developing therapeutic strategies, anti-MEK-2 antibody (96) offers the performance and reliability needed for advanced biomedical research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MEK-2 Antibody (96) | sc-136261 | 50 µg/0.5 ml | $322.00 |