MEK-1/2 Antibody (9G3): sc-81504

MEK-1/2 Antibody (9G3) is a mouse monoclonal IgG2a antibody that detects MEK-1/2 protein of mouse, rat, human, and canine origin by western blotting (WB) and immunoprecipitation (IP). Anti-MEK-1/2 antibody (9G3) is available as the non-conjugated format. MEK-1 and MEK-2 proteins play a crucial role in the mitogen-activated protein kinase (MAPK) signaling pathway, essential for various cellular processes, including proliferation, differentiation, and survival. MEK-1 and MEK-2 proteins are located in the cytoplasm and activate in response to extracellular signals, leading to phosphorylation of downstream MAP kinases such as ERK. Proper functioning of MEK-1 and MEK-2 remains vital, as dysregulation of this pathway can contribute to various diseases, including cancer. MEK-1 and MEK-2 interact with other proteins in the signaling cascade, such as Raf kinases, further underscoring their importance in cellular signaling networks. Anti-MEK-1/2 antibody (9G3) enables valuable insights into the dynamics of the MAPK pathway and its implications in health and disease.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MEK-1/2 Antibody (9G3) has 52 citations in a variety of scientific publications.

Primary antibodies like Anti-MEK-1/2 Antibody (9G3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MEK-1/2 Antibody (9G3) Specifications

Alternate Product Name: MAP2K1, MAP2K2

Product Clone Name: 9G3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: MEK-1/2

Epitope Species: human

Product Reactivity/Detection: the activation loop of MEK-1 and MEK-2 (independent of its phosphorylation status)

Species Reactivity/Detection: mouse, rat, human, canine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 50 µg IgG_2a in 0.5 ml of PBS with < 0.1% sodium azide, 0.1% gelatin, PEG and sucrose

Research Citations: 52 citations in various scientific publications

Available Conjugates/Forms for MEK-1/2 Antibody (9G3): N/A