Anti-megsin Anticuerpo H-10 es un monoclonal de ratón IgG1 (kappa light chain) megsin Anticuerpo proporcionado como 200 µg/ml
Producido contra los amino ácidos 32-165 cerca de el N-terminus de megsin de origen human
megsin Anticuerpo (H-10) es recomendado para detectar megsin de mouse, rat y human origen, mediante WB, IP, IF y ELISA
megsin Anticuerpo (H-10) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de megsin (H-10): sc-515694.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for megsin Antibody (H-10) for WB applications. These reagents are now offered in bundles with megsin Antibody (H-10) (see ordering information below).
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megsin Antibody (H-10) is a high quality monoclonal megsin antibody (also designated megsin antibody) suitable for the detection of the megsin protein of mouse, rat and human origin. megsin Antibody (H-10) is available as both the non-conjugated anti-megsin antibody form, as well as multiple conjugated forms of anti-megsin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Megsin, also designated SerpinB7 and TP55, is a 380 amino acid cytoplasmic protein that is predominantly expressed in mesangial cells, which play an important role in maintaining glomerular structure and function. As a member of the serpin family, megsin is a serine protesase inhibitor which potentially inactivate MMP-2, MMP-9 and plasmin, proteins that are notably responsible for degradation of extracellular matrix. Overexpression of megsin results in an increase in number of mesangial cells and therefore a progressive mesangial matrix expansion, which is accompanied by immune complex deposition. This finding suggests that megsin significantly influences the role of mesangial cells in renal structure and is likely implicated in a variety of nephropathies.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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