Latexin Antibody (199CT6.1.2): sc-517339
- Latexin Antibody (199CT6.1.2) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against a recombinant protein corresponding to Latexin of human origin
- recommended for detection of Latexin of mouse, rat and human origin by WBIP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Latexin Antibody (199CT6.1.2). This work is in progress.
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Latexin Antibody (199CT6.1.2) is a mouse monoclonal IgG1 antibody that detects Latexin in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. Latexin, also known as endogenous carboxypeptidase inhibitor (ECI) or tissue carboxypeptidase inhibitor (TCI), is a member of the protease inhibitor I47 family and serves as a non-competitive, reversible inhibitor of metallocarboxypeptidases (MCPs) such as CPA1, CPA2, and CPA4. Latexin is predominantly expressed in various tissues, including the heart, prostate, pancreas, ovary, kidney, brain, and colon, highlighting its significance in multiple physiological processes. The structure of Latexin is characterized by two topologically equivalent subdomains that allow binding to MCPs with low specificity, providing the versatility to inhibit all vertebrate A/B MCPs. This structural feature is crucial as Latexin modulates the activity of these enzymes, which are involved in critical biological functions such as protein processing and regulation of inflammatory responses. By understanding Latexin′s role in pain transmission and inflammation, researchers can explore potential implications in various pathological conditions, making anti-Latexin antibody (199CT6.1.2) an essential tool for studying these processes in the laboratory.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Latexin Antibody (199CT6.1.2) | sc-517339 | 100 µg/ml | $322.00 |