Molecular structure of iso-Tacrolimus
iso-Tacrolimus (CAS 134590-88-8)
Alternate Names:
Tacrolimus Lactone Isomer
CAS Number:
134590-88-8
Molecular Weight:
804.02
Molecular Formula:
C44H69NO12
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Iso-Tacrolimus is a macrolide lactone compound that inhibits T-lymphocyte activation and proliferation by binding to the intracellular protein, FKBP-12. This complex inhibits the activity of calcineurin, which is a key enzyme in the production of interleukin-2, a cytokine that promotes the growth and differentiation of T-cells. By inhibiting this pathway, iso-Tacrolimus effectively suppresses the immune response. Iso-Tacrolimus has anti-inflammatory and anti-proliferative effects, making it valuable in the field of immunosuppression.
iso-Tacrolimus (CAS 134590-88-8) References
- Chemistry of the immunomodulatory macrolide ascomycin and related analogues. | Bulusu, MA., et al. 2011. Prog Chem Org Nat Prod. 94: 59-126. PMID: 21833838
Inhibitor of:
BTN3A1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
iso-Tacrolimus, 0.5 mg | sc-489258 | 0.5 mg | $448.00 | |||
iso-Tacrolimus, 1 mg | sc-489258A | 1 mg | $676.00 |