Integrin α5/ITGA5/CD49e Antibody (D-9): sc-166666

Integrin α5 Antibody (D-9) is a mouse monoclonal IgG2a antibody that detects Integrin α5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Integrin α5 plays a crucial role in cell adhesion and is primarily located on the cell surface, where Integrin α5 forms heterodimers with the β1 subunit to create the α5β1 integrin receptor. This receptor is essential for binding to extracellular matrix components like fibronectin, which is vital for various cellular processes, including tissue repair, cell migration, and differentiation. Integrin α5 on the cell surface facilitates interaction with the extracellular matrix, promoting cellular signaling pathways that influence cell behavior and function. Furthermore, Integrin α5′s ability to cluster and interact with other integrins enhances signaling capacity, making Integrin α5 a key player in the regulation of cellular responses to the extracellular environment. Anti-Integrin α5 antibody (D-9) is an invaluable tool for researchers studying the dynamics of cell adhesion and signaling in various biological contexts.

The preferred Integrin α5/ITGA5/CD49e antibody is Integrin α5/ITGA5/CD49e Antibody (P1D6): sc-13547.