Molecular structure of Ibuprofen Acyl-β-D-glucuronide, CAS Number: 115075-59-7
Ibuprofen Acyl-β-D-glucuronide (CAS 115075-59-7)
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Alternate Names:
1-[α-Methyl-4-(2-methylpropyl)benzeneacetate] β-D-Glucopyranuronic Acid; Ibuprofen glucuronide
Application:
Ibuprofen Acyl-β-D-glucuronide is a glucuronide metabolite of Ibuprofen
CAS Number:
115075-59-7
Purity:
≥98%
Molecular Weight:
382.40
Molecular Formula:
C19H26O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ibuprofen Acyl-β-D-glucuronide is a potent and selective agonist of the CB1 receptor, which is responsible for the psychoactive effects of cannabis. This receptor is involved in a wide range of physiological processes, including pain perception, appetite regulation, and mood modulation. By selectively activating this receptor, researchers can gain insight into the underlying mechanisms of these processes. Ibuprofen Acyl-β-D-glucuronide is also useful in organic synthesis.
Ibuprofen Acyl-β-D-glucuronide (CAS 115075-59-7) References
- Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. | Koga, T., et al. 2011. Drug Metab Dispos. 39: 54-60. PMID: 20926620
- Glucuronides as Potential Anionic Substrates of Human Cytochrome P450 2C8 (CYP2C8). | Ma, Y., et al. 2017. J Med Chem. 60: 8691-8705. PMID: 28653847
- In vitro inhibition of human UGT isoforms by ritonavir and cobicistat. | Algeelani, S., et al. 2018. Xenobiotica. 48: 764-769. PMID: 28891378
- Seasonal and ageing effect on the behaviour of 86 drugs in a full-scale surface treatment wetland: Removal efficiencies and distribution in plants and sediments. | Nuel, M., et al. 2018. Sci Total Environ. 615: 1099-1109. PMID: 29751415
- In Vivo Metabolism of Ibuprofen in Growing Conventional Pigs: A Pharmacokinetic Approach. | Millecam, J., et al. 2019. Front Pharmacol. 10: 712. PMID: 31316382
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ibuprofen Acyl-β-D-glucuronide, 1 mg | sc-211625 | 1 mg | $327.00 |