Anti-HIF-1 alpha Anticuerpo 28b es un monoclonal de ratón IgG1 κ HIF-1α Anticuerpo, ver las 180 publicaciones, proporcionado como 200 µg/ml
epitope mapping within amino acids 329-530 of HIF-1α of human origin
HIF-1 alpha Anticuerpo (28b) es recomendado para detectar HIF-1α de mouse, rat y human origen, mediante WB, IP, IF y IHC(P); también reactivo con otras especies, incluyendo anyd bovine and porcine
HIF-1 alpha Anticuerpo (28b) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
TransCruz reactivo para Gel Supershift y ChIP (sc-13515 X, 200 µg/0.1 ml)
Contacte con nosotros para recibir GRATIS 10 µg de muestra de HIF-1α (28b): sc-13515.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for HIF-1α Antibody (28b) for WB and IHC(P) applications. This reagent is now offered in a bundle with HIF-1α Antibody (28b) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
HIF-1α Antibody (28b) is a high quality monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the detection of the HIF-1 alpha protein of mouse, rat and human origin. HIF-1α Antibody (28b) is available as both the non-conjugated anti-HIF-1 alpha antibody form, as well as multiple conjugated forms of anti-HIF-1 alpha antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1α, HIF-1β (also designated Arnt 1), EPAS-1 (also designated HIF-2α) and HIF-3α, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1α is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription. Hypoxia-inducible expression of some genes such as Glut-1, p53, p21 or Bcl-2, is HIF-1α dependent, whereas expression of others, such as p27, GADD 153 or HO-1, is HIF-1α independent. EPAS-1 and HIF-3α have also been shown to form heterodimeric complexes with Arnt 1 in response to hypoxia.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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