GSK-3 beta Anticuerpo 11B9 es un monoclonal de ratón IgG1, ver las 66 publicaciones, proporcionado como 50 µg/0.5 ml
producido contra el N-terminus de GSK-3β de origen human
recomendado para detectarGSK-3β de mouse, rat y human origen, mediante WB y IP; también reactivo con otras especies, incluyendo canine
Ver GSK-3α/β (0011-A): sc-7291 para GSK-3β anticuerpos conjugados, incluyendo AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 y 790.
Contacte con nosotros para recibir GRATIS 10 µg de muestra de GSK-3β (11B9): sc-81462.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for GSK-3β Antibody (11B9) for WB applications. These reagents are now offered in bundles with GSK-3β Antibody (11B9) (see ordering information below).
GSK para análisis funcionales de las repuestas celulares a GSK
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Glycogen synthase kinase 3, or GSK-3, is a serine/threonine, proline-directed kinase involved in a diverse array of signaling pathways, including glycogen synthesis and cellular adhesion, and has been implicated in Alzheimer′s disease. Two forms of GSK-3, designated GSK-3α and GSK-3β, have been identified and differ in their subcellular localization. Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyper-phosphorylated in paired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheimer′s disease (5,6). Hyperphosphorylation of Tau is thought to be the critical event leading to the assembly of PHF. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK-3. This presents the possibility that miscues in GSK-3 signaling contribute to the onset of Alzheimer′s disease..
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.