Gros1 Antibody (F-07): sc-101240

Gros1 Antibody (F-07) is a mouse monoclonal IgG2a antibody that detects Gros1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Gros1, also known as leprecan, is a leucine proline-enriched basement membrane-associated proteoglycan that plays a crucial role in the structural integrity and function of the basement membrane, which is essential for tissue organization and cellular signaling. Gros1 is primarily located at the epithelial/mesenchymal interface, where anti-Gros1 antibody (F-07) can detect its contribution to the formation of a specialized extracellular matrix that varies in composition depending on the tissue type and developmental stage. Gros1 is vital for processes such as cell adhesion, migration, and differentiation, making Gros1 (F-07) antibody a key tool in studying tissue repair and development. Notably, Gros1 is alternatively spliced to produce two isoforms, Gros1S and Gros1L, with Gros1S being predominantly expressed in the placenta, ovary, and testis, highlighting its importance in reproductive biology. The rat homolog of Gros1 is secreted by parietal yolk sac tumor cells and facilitates the generation of substrates necessary for protein glycosylation, further underscoring the functional significance of this proteoglycan in cellular processes. Gros1 monoclonal antibody (F-07) serves as an invaluable tool for researchers investigating the roles of this protein in various biological contexts.

The preferred Gros1 antibody is Gros1 Antibody (F-5): sc-393003.