GLTSCR1 Antibody (H-10): sc-515086
- GLTSCR1 Antibody (H-10) is a mouse monoclonal IgG1 κ GLTSCR1 antibody, cited in 8 publications, provided at 200 µg/ml
- raised against amino acids 506-574 mapping within an internal region of GLTSCR1 of human origin
- GLTSCR1 Antibody (H-10) is recommended for detection of GLTSCR1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-GLTSCR1 Antibody (H-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for GLTSCR1 Antibody (H-10) for WB applications. This reagent is now offered in a bundle with GLTSCR1 Antibody (H-10) (see ordering information below).
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GLTSCR1 Antibody (H-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects GLTSCR1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-GLTSCR1 antibody (H-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GLTSCR1, also known as glioma tumor suppressor candidate region gene 1 protein, consists of 1,560 amino acids and plays a crucial role in tumor suppression, particularly in prostate carcinoma, where a polymorphism in GLTSCR1 gene has been linked to increased disease aggressiveness. GLTSCR1 is expressed at moderate levels in vital tissues such as heart, brain, placenta, skeletal muscle, and pancreas, while exhibiting lower expression in lung, liver, and kidney. Conservation of GLTSCR1 across species, including humans, chimpanzees, mice, and rats, underscores fundamental biological importance. Additionally, GLTSCR1 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 19q13.32, a region known for high gene density and housing numerous immunoglobulin superfamily members, which are critical for immune response and cellular communication.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GLTSCR1 Antibody (H-10) References:
- A transcript map of the chromosome 19q-arm glioma tumor suppressor region. | Smith, JS., et al. 2000. Genomics. 64: 44-50. PMID: 10708517
- Multiple single nucleotide polymorphisms on human chromosome 19q13.2-3 associate with risk of Basal cell carcinoma. | Yin, J., et al. 2002. Cancer Epidemiol Biomarkers Prev. 11: 1449-53. PMID: 12433725
- Polymorphisms in GLTSCR1 and ERCC2 are associated with the development of oligodendrogliomas. | Yang, P., et al. 2005. Cancer. 103: 2363-72. PMID: 15834925
- The extended human leukocyte receptor complex: diverse ways of modulating immune responses. | Barrow, AD. and Trowsdale, J. 2008. Immunol Rev. 224: 98-123. PMID: 18759923
- DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma. | Rajaraman, P., et al. 2010. Neuro Oncol. 12: 37-48. PMID: 20150366
- The pregnancy-specific glycoprotein (PSG) gene cluster on human chromosome 19: fine structure of the 11 PSG genes and identification of 6 new genes forming a third subgroup within the carcinoembryonic antigen (CEA) family. | Teglund, S., et al. 1994. Genomics. 23: 669-84. PMID: 7851896
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GLTSCR1 Antibody (H-10) | sc-515086 | 200 µg/ml | $322.00 | |||
GLTSCR1 Antibody (H-10): m-IgG Fc BP-HRP Bundle | sc-526416 | 200 µg Ab; 10 µg BP | $361.00 | |||
GLTSCR1 Antibody (H-10) AC | sc-515086 AC | 500 µg/ml, 25% agarose | $424.00 | |||
GLTSCR1 Antibody (H-10) HRP | sc-515086 HRP | 200 µg/ml | $322.00 | |||
GLTSCR1 Antibody (H-10) FITC | sc-515086 FITC | 200 µg/ml | $336.00 | |||
GLTSCR1 Antibody (H-10) PE | sc-515086 PE | 200 µg/ml | $349.00 | |||
GLTSCR1 Antibody (H-10) Alexa Fluor® 488 | sc-515086 AF488 | 200 µg/ml | $364.00 | |||
GLTSCR1 Antibody (H-10) Alexa Fluor® 546 | sc-515086 AF546 | 200 µg/ml | $364.00 | |||
GLTSCR1 Antibody (H-10) Alexa Fluor® 594 | sc-515086 AF594 | 200 µg/ml | $364.00 | |||
GLTSCR1 Antibody (H-10) Alexa Fluor® 647 | sc-515086 AF647 | 200 µg/ml | $364.00 | |||
GLTSCR1 Antibody (H-10) Alexa Fluor® 680 | sc-515086 AF680 | 200 µg/ml | $364.00 | |||
GLTSCR1 Antibody (H-10) Alexa Fluor® 790 | sc-515086 AF790 | 200 µg/ml | $364.00 |