FTα Antibody (IB7): sc-23906

FTα Antibody (IB7) is a mouse monoclonal IgG1 kappa light chain antibody that detects FTα protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). Anti-FTα antibody (IB7) plays a crucial role in studying the function of farnesyl transferases, which are essential for the post-translational modification of proteins through the addition of farnesyl groups. This modification is vital for the proper localization and function of various proteins, including nuclear lamins and the oncogene p21Ras, which are involved in critical cellular processes such as signal transduction and cell division. The farnesylation process ensures that these proteins are anchored to cellular membranes, facilitating their interaction with other signaling molecules and cellular structures. Understanding the dynamics of farnesyl transferase activity and its substrates can provide insights into various diseases, including cancer, where aberrant farnesylation can lead to uncontrolled cell growth and proliferation. FTα monoclonal antibody (IB7) serves as an invaluable tool for researchers investigating the mechanisms of protein modification and their implications in health and disease.

The preferred FTα antibody is FTα Antibody (D-5): sc-374262.