Fmoc-D-Dap(Boc)-OH (CAS 198544-42-2)
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Fmoc-D-Dap(Boc)-OH is used extensively in the field of peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a temporary protector for the amino functionality, allowing for its selective deprotection under basic conditions without disturbing other protected groups. The D-Dap (D-diaminopropionic acid) portion of the molecule introduces a secondary amine, which can be further functionalized or participate in peptide bond formation. The Boc (tert-butoxycarbonyl) group on the side chain amine provides orthogonal protection, which can be removed under acidic conditions independently of the Fmoc group. This dual protection strategy is critical in the stepwise construction of peptides, enabling the introduction of multiple amino acids with high fidelity. Researchers use Fmoc-D-Dap(Boc)-OH to study the synthesis of peptides that contain non-standard amino acids, which are important in the development of novel materials and bioactive compounds.
Fmoc-D-Dap(Boc)-OH (CAS 198544-42-2) References
- Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase. | Tseng, CC., et al. 2002. Biochemistry. 41: 13350-9. PMID: 12416979
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fmoc-D-Dap(Boc)-OH, 1 g | sc-294803 | 1 g | $195.00 | |||
Fmoc-D-Dap(Boc)-OH, 5 g | sc-294803A | 5 g | $750.00 |