FMIP Antibody (E-3): sc-514192
- FMIP Antibody (E-3) is a mouse monoclonal mouse IgM κ κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 36-57 near the N-terminus of FMIP of mouse origin
- recommended for detection of FMIP of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for FMIP Antibody (E-3) for WB applications. This reagent is now offered in a bundle with FMIP Antibody (E-3) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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FMIP Antibody (E-3) is a mouse monoclonal IgM antibody that detects FMIP in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FMIP, or Fms-interacting protein, plays a crucial role in regulating myeloid progenitor cell differentiation, particularly in macrophage and granulocyte lineage commitment. FMIP (E-3) antibody targets proteins primarily located in progenitor cell cytoplasm, where FMIP interacts with macrophage colony-stimulating factor receptor, c-Fms. This interaction influences signaling pathways that determine progenitor cell differentiation into macrophages or granulocytes. Low endogenous FMIP levels promote macrophage differentiation upon M-CSF signaling, while FMIP overexpression can lead to c-Fms saturation, resulting in a shift towards granulocyte differentiation. FMIP′s ability to modulate these pathways underscores its importance in hematopoiesis and immune response, making anti-FMIP antibody (E-3) an essential tool for researchers studying blood cell development and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FMIP Antibody (E-3) | sc-514192 | 200 µg/ml | $322.00 | |||
FMIP Antibody (E-3): m-IgGκ BP-HRP Bundle | sc-552648 | 200 µg Ab; 40 µg BP | $361.00 | |||
FMIP (E-3) Neutralizing Peptide | sc-514192 P | 100 µg/0.5 ml | $69.00 |