Anti-Flg/FGFR1 Anticuerpo M2F12 es un monoclonal de ratón IgG2a κ Flg/FGFR1 Anticuerpo, ver las 12 publicaciones, proporcionado como 200 µg/ml
raised against the ectodomain of Flg isoform α of human origin
Flg/FGFR1 Anticuerpo (M2F12) es recomendado para detectar Flg isoform α de mouse, rat y human origen, mediante WB, IP, IF y IHC(P)
Flg/FGFR1 Anticuerpo (M2F12) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de Flg/FGFR1 (M2F12): sc-57132.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) is the preferred secondary detection reagent for Flg/FGFR1 Antibody (M2F12) for WB and IHC(P) applications. This reagent is now offered in a bundle with Flg/FGFR1 Antibody (M2F12) (see ordering information below).
Flg para análisis funcionales de las repuestas celulares a Flg
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Flg Antibody (M2F12) is a high quality monoclonal Flg antibody (also designated FGFR1 antibody, or fibroblast growth factor receptor 1 antibody) suitable for the detection of the Flg protein of mouse, rat and human origin. Flg Antibody (M2F12) is available as both the non-conjugated anti-Flg antibody form, as well as multiple conjugated forms of anti-Flg antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. These include the Flg receptor (FGFR-1), the Bek receptor (FGFR-2), FGFR-3, FGFR-4, FGFR-5 and FGFR-6. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The gene encoding human Flg maps to chromosome 8p12 and is alternatively spliced to produce several isoforms. Mutations in Flg are associated with Pfeiffer syndrome (a skeletal disorder characterized by craniosynostosis with deviation and enlargement of the thumbs and great toes), brachymesophalangy with phalangeal ankylosis and a varying degree of soft tissue syndactyly. The Flg gene is also involved in chromosomal translocations with ZNF198, CEP110 and FOP, which may lead to stem cell leukemia lymphoma (SCLL).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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