Fibrinogen Antibody (27C8): sc-51894
- Fibrinogen Antibody (27C8) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against fibrin degradation products of human origin
- recommended for detection of whole Fibrinogen, consisting of a dimer of three pairs of non-identical chains, α, β and γ, and Fibrin degradation products of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Fibrinogen Antibody (27C8). This work is in progress.
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Fibrinogen Antibody (27C8) is a mouse monoclonal IgG2a antibody that detects Fibrinogen in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Fibrinogen is a crucial plasma glycoprotein synthesized in the liver, consisting of three structurally distinct subunits: α, β, and γ. Fibrinogen plays a vital role in the coagulation cascade, particularly in platelet aggregation and the formation of Fibrin, which is essential for blood clotting. Fibrinogen′s importance extends beyond structural roles; Fibrinogen is involved in regulating plasma viscosity and erythrocyte aggregation, making Fibrinogen a key player in maintaining hemostasis during tissue injury. Upon vascular damage, Fibrinogen is cleaved by Thrombin, resulting in the formation of Fibrin, the primary component of blood clots. Additionally, Fibrinogen cleavage products have significant biological activities, including the regulation of cell adhesion and spreading, as well as exhibiting vasoconstrictor and chemotactic properties. These functions underscore Fibrinogen′s importance in both hemostatic processes and inflammatory responses, highlighting Fibrinogen′s relevance in various pathological conditions. Anti-Fibrinogen antibody (27C8) is an invaluable tool for researchers studying coagulation and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibrinogen Antibody (27C8) | sc-51894 | 100 µg/ml | $322.00 |