This polyclonal antibody has been discontinued. See our recommended Elongin C (56) monoclonal antibody (sample data shown).
Elongin C Antibody (R-20): sc-1559
- Elongin C Antibody (R-20) is a goat polyclonal IgG; 200 µg/ml
- epitope mapping at the C-terminus of Elongin C of human origin
- Discontinued polyclonal antibody
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Description
Individuals harboring germline mutations in the tumor suppressor gene von Hippel-Lindau (VHL) exhibit an increased susceptibility to a variety of tumors including renal carcinoma, hemangio-blastoma of the central nervous system and pheochromo-cytoma. The Elongin (SIII) complex has been identified as the functional target of the VHL protein. Elongin (SIII) is a heterotrimer composed of a transcriptional active subunit designated Elongin A and two regulatory subunits designated Elongin B and Elongin C. VHL functions by binding to the Elongin B and C subunits, inhibiting the transcriptional efficacy of the Elongin (SIII) complex.
Ordering Information
Elongin C (56): sc-135895 [ Recommended monoclonal replacement for Elongin C (R-20) ]
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Elongin C Antibody (56) | sc-135895 | 200 µg/ml | $322.00 | |||
Elongin C Antibody (56): m-IgG Fc BP-HRP Bundle | sc-539887 | 200 µg Ab; 10 µg BP | $361.00 | |||
Elongin C Antibody (56): m-IgG1 BP-HRP Bundle | sc-541764 | 200 µg Ab; 20 µg BP | $361.00 |