Anti-DECR1 Anticuerpo G-10 es un monoclonal de ratón IgG1 (kappa light chain) DECR1 Anticuerpo proporcionado como 200 µg/ml
producido contra los amino ácidos 90-335 localizados en el C-terminus de DECR1 de origen human
DECR1 Anticuerpo (G-10) es recomendado para detectar DECR1 de human y avian origen, mediante WB, IP, IF, IHC(P) y ELISA; también reactivo con otras especies, incluyendo anyd equine, canine, bovine, porcine and avian
DECR1 Anticuerpo (G-10) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Ver m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), nuestras altamente recomendadas alternativa a los anticuerpos secundarios convencionales, anti-IgG de ratón.
Contacte con nosotros para recibir GRATIS 10 µg de muestra de DECR1 (G-10): sc-393473.
DECR1 para análisis funcionales de las repuestas celulares a DECR
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DECR1 Antibody (G-10) is a high quality monoclonal DECR1 antibody (also designated DECR1 antibody) suitable for the detection of the DECR1 protein of human origin. DECR1 Antibody (G-10) is available as both the non-conjugated anti-DECR1 antibody form, as well as multiple conjugated forms of anti-DECR1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Beta oxidation refers to the enzymatic process by which Acyl-CoA is catalytically broken down to yield Acetyl-CoA, the first molecule required for the Krebs cycle. DECR1 (2,4-dienoyl-CoA reductase, mitochondrial), also known as DECR, is a 335 amino acid mitochondrial protein that exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. Expressed in heart, pancreas, liver, lung, kidney and skeletal muscle, DECR1 functions as an auxiliary enzyme of beta-oxidation where it participates in the metabolism of unsaturated fatty enoyl-CoA esters. Specifically, DECR1 uses NADP+ to catalyze the reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA, which can then be used as an intermediate in the Krebs cycle. Additionally, DECR1 is thought to function as a tumor suppressor, possibly down regulating the expression of Neu and slowing the rate of tumorigenesis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Can DECR1 Antibody (G-10): sc-393473, used to detect mouse Decr1?
Preguntado por: AmrGhanam
Thank you for your question. We have not yet tested this antibody in mouse samples, and so that is not a recommended species at this time.
Respondida por: Technical Support
Fecha de publicación: 2019-04-13
Can DECR1 (G-10): sc-393473 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Preguntado por: Professor Griffin
Thank you for your question. Yes, DECR1 (G-10): sc-393473 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Rated 5 de
Very good Western blot data of DECR1 expressionVery good Western blot data of DECR1 expression in Hep G2, RT-4 and U-251-MG whole cell lysates and human heart and human liver tissue extracts. -SCBT QC
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