cyclin B2 Antibody (X121.10): sc-53239

Cyclin B2 Antibody (X121.10) is a mouse monoclonal IgG1 antibody that detects cyclin B2 in species reactivity x through applications such as western blotting (WB) and immunoprecipitation (IP). Cyclin B2 plays a crucial role in the regulation of the cell cycle, particularly during the transition from the G2 phase to mitosis, by forming a complex with the Cdc2 protein kinase, which is essential for the activation of maturation-promoting factor. This complex is vital for the proper progression of mitosis, as cells divide accurately and efficiently. Cyclin B2 is primarily located in the cytoplasm and translocates to the nucleus as cells prepare to enter mitosis, highlighting cyclin B2′s importance in cell cycle regulation and the timing of mitotic entry. Furthermore, cyclin B2 undergoes various post-translational modifications, including phosphorylation, which can influence stability and activity, thereby impacting cell cycle progression. Anti-cyclin B2 antibody (X121.10) is an invaluable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying mitotic regulation.

The preferred cyclin B2 antibody is cyclin B2 Antibody (A-2): sc-28303.