Date published: 2026-5-5
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CEACAM5 Antibody (26/3/13) - Western Blotting - Image 14582
CEACAM5 Antibody (26/3/13): sc-59872. Western blot analysis of CEACAM5 expression in LS1034 whole cell lysate under reducing (A) and non-reducing (B) conditions.
CEACAM5 Antibody (26/3/13) - Western Blotting - Image 14582
CEACAM5 Antibody (26/3/13): sc-59872. Western blot analysis of CEACAM5 expression in LS1034 whole cell lysate under reducing (A) and non-reducing (B) conditions.
CEACAM5 Antibody (26/3/13): sc-59872. Western blot analysis of CEACAM5 expression in LS1034 whole cell lysate under reducing (A) and non-reducing (B) conditions.

CEACAM5 Antibody (26/3/13): sc-59872

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Datasheets
  • CEACAM5 Antibody (26/3/13) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against full length native CEACAM5 of human origin
  • recommended for detection of CEACAM5 of human origin by WB, IP, IF, FCM and ELISA
  • available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • See CEACAM5 (CI-P83-1): sc-23928 for CEACAM5 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CEACAM5 Antibody (26/3/13) for WB applications. These reagents are now offered in bundles with CEACAM5 Antibody (26/3/13) (see ordering information below).
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    Additional CEACAM Antibodies including CEACAM1, CEACAM16, CEACAM19, CEACAM2, CEACAM20, CEACAM3, CEACAM6 and CEACAM7

    CEACAM5 Antibody (26/3/13) is a mouse monoclonal IgG1 antibody that detects CEACAM5 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CEACAM5, also known as carcinoembryonic antigen (CEA), is a heavily glycosylated glycoprotein that plays a crucial role in cell adhesion and is predominantly expressed in epithelial tissues. CEACAM5 expression is significantly upregulated in various tumors, making anti-CEACAM5 antibody (26/3/13) an important tool for cancer diagnosis and monitoring. CEACAM5 is located on the cell surface, where CEACAM5 participates in intercellular adhesion processes, facilitating communication between cells and influencing tumor progression. CEACAM5 presence in the bloodstream is often associated with malignancies, particularly colorectal cancer, and CEACAM5 levels can indicate disease status, highlighting CEACAM5 (26/3/13) antibody′s importance in clinical oncology. Anti-CEACAM5 antibody (26/3/13) serves as an essential tool for researchers studying cancer biology and cell adhesion mechanisms, providing valuable insights into tumor behavior and potential therapeutic targets.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    CEACAM5 Antibody (26/3/13) References:

    1. Platelet Carcinoembryonic Antigen Cell Adhesion Molecule 5 (CEACAM5) as a Possible Novel Diagnostic Tool for Evaluation of Acute Coronary Syndrome.  |  Wan, W., et al. 2019. Med Sci Monit. 25: 9864-9874. PMID: 31865362
    2. Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5-SN38 Antibody-drug Conjugate in Neuroendocrine Prostate Cancer.  |  DeLucia, DC., et al. 2021. Clin Cancer Res. 27: 759-774. PMID: 33199493
    3. Elevated CEACAM5 Levels in Patients with Asthma.  |  Xu, C., et al. 2022. Int Arch Allergy Immunol. 183: 673-681. PMID: 35172310
    4. A Small CEACAM5 Peptide Restores the Protective Function of CD8+ Regulatory T Cells in Crohn's Disease.  |  Dunkin, D., et al. 2022. Gastroenterology. 163: 1090-1093.e3. PMID: 35700774
    5. CEACAM5 is an IL-13-regulated epithelial gene that mediates transcription in type-2 (T2) high severe asthma.  |  Mumby, S., et al. 2022. Allergy. 77: 3463-3466. PMID: 35916059
    6. CT109-SN-38, a Novel Antibody-drug Conjugate with Dual Specificity for CEACAM5 and 6, Elicits Potent Killing of Pancreatic Cancer Cells.  |  Cardenas, KCA., et al. 2024. Curr Cancer Drug Targets. 24: 720-732. PMID: 38178674
    7. A Multimode Microfiber Specklegram Biosensor for Measurement of CEACAM5 through AI Diagnosis.  |  Liu, Y., et al. 2024. Biosensors (Basel). 14: PMID: 38275310
    8. SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.  |  Luo, Y., et al. 2024. Front Immunol. 15: 1303356. PMID: 38686388
    9. CEACAM5-Targeted Immuno-PET in Androgen Receptor-Negative Prostate Cancer.  |  Imberti, C., et al. 2024. J Nucl Med. 65: 1043-1050. PMID: 38782457
    10. Structural insights into epitope-paratope interactions of a monoclonal antibody targeting CEACAM5-expressing tumors.  |  Kumar, A., et al. 2024. Nat Commun. 15: 9377. PMID: 39477960

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    CEACAM5 Antibody (26/3/13)

    sc-59872
    200 µg/ml
    		$322.00

    CEACAM5 Antibody (26/3/13): m-IgG Fc BP-HRP Bundle

    sc-539146
    200 µg Ab; 10 µg BP
    		$361.00

    CEACAM5 Antibody (26/3/13): m-IgG1 BP-HRP Bundle

    sc-541293
    200 µg Ab; 20 µg BP
    		$361.00

    CEACAM5 Antibody (26/3/13) FITC

    sc-59872 FITC
    200 µg/ml
    		$336.00

    CEACAM5 Antibody (26/3/13) PE

    sc-59872 PE
    200 µg/ml
    		$349.00

    How can CEACAM5 (26/3/13): sc-59872 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

    Asked by: Professor Griffin
    In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-59872 PE) or fluoroscein (sc-59872 FITC).
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_5, d_5, h_11CST
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    Rated 5 out of 5 by from CEACAM5 Antibody (26/3/13)Our lab finds this clone completely specific to CEACAM5 among cell surface displayed CEACAM1/3/5/6/7/8/20. (CEACAM4/16/19/21 not tested due to lower similarity). Detects rh CEACAM5 in ELISA and cell displayed CEACAM5 by flow cytometry. maximum MFI in flow titrations not as high as some other CEACAM5 antibodies, but EC50 is comparable. Originally part of genovac series. Epitope probably lies in N terminal IgV domain (based on binning, not confirmed)
    Date published: 2025-12-08
    Rated 4 out of 5 by from Positive results in western blot analysisPositive results in western blot analysis of CEACAM5 expression in LS1034 whole cell lysate under reducing and non-reducing conditions. -SCBT QC
    Date published: 2014-07-02
    • y_2026, m_5, d_5, h_11
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    CEACAM5 Antibody (26/3/13) is rated 4.5 out of 5 by 2.
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