Cdc6 Antibody (0.N.189): sc-70827

Cdc6 Antibody (0.N.189) is a mouse monoclonal IgG1 antibody that detects Cdc6 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Cdc6 plays a crucial role in the initiation of DNA replication, acting as a regulatory factor that ensures proper timing of DNA synthesis during the cell cycle. Cdc6 function is vital for maintaining genomic stability, as Cdc6 helps prevent premature or inappropriate DNA replication, which can lead to genomic instability and contribute to tumorigenesis. Cdc6 is primarily located in the nucleus, where Cdc6 associates with the origin recognition complex to facilitate helicase loading onto DNA, thereby marking sites for replication initiation. Understanding Cdc6 dynamics and regulatory mechanisms is essential for elucidating processes of cell division and potential implications in cancer biology. Anti-Cdc6 antibody (0.N.189) is an invaluable tool for researchers studying cell cycle regulation and associated pathways, providing insights into molecular underpinnings of cellular proliferation and development of therapeutic strategies targeting cell cycle dysregulation.

The preferred Cdc6 antibody is Cdc6 Antibody (180.2): sc-9964.