CD81 Antibody (D-4): sc-166028

CD81 Antibody (D-4) is a mouse monoclonal IgG2b kappa light chain antibody engineered to target CD81, also known as TAPA-1. CD81 monoclonal antibody (D-4) is raised against amino acids 90-210 of human CD81 and demonstrates reactivity with CD81 from mouse, rat, and human species, making CD81 (D-4) antibody suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CD81 is a type III transmembrane protein located primarily on the plasma membrane, where CD81 plays a pivotal role in cell signaling and communication. CD81′s strategic position within the cell membrane allows CD81 to facilitate interactions between cells and their environment, which is essential for processes such as cell growth, differentiation, and immune responses. CD81 is widely expressed on cells of hematopoietic, neuroectodermal, and mesenchymal origin, highlighting CD81′s importance across various biological systems. CD81 forms multimolecular complexes by associating with other proteins like CD37 and CD53, and on B cells, CD81 interacts with CD19, CD21, and MHC class II antigens, which are crucial for the regulation of immune responses. CD81′s ability to mediate these interactions underscores CD81′s significance in maintaining cellular homeostasis and effective immune function. CD81 (D-4) monoclonal antibody is available in both non-conjugated and various conjugated forms, including horseradish peroxidase (HRP) and fluorescent labels, providing flexibility for diverse research applications.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CD81 Antibody (D-4) has 33 citations in a variety of scientific publications.

Primary antibodies like Anti-CD81 Antibody (D-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CD81 Antibody (D-4) Specifications

Alternate Product Name: TAPA1

Product Clone Name: D-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 90-210

Epitope Target: CD81

Epitope Species: human

Product Reactivity/Detection: CD81

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 33 citations in various scientific publications

Available Conjugates/Forms for CD81 Antibody (D-4): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred CD81 antibody is CD81 Antibody (1.3.3.22): sc-7637.