cAMP Antibody (9H4C4): sc-130063

cAMP Antibody (9H4C4) is a mouse monoclonal IgG1 antibody that detects cAMP in non-species reactive samples by enzyme-linked immunosorbent assay (ELISA). cAMP, or cyclic adenosine monophosphate, serves as a crucial second messenger in various signal transduction pathways, playing a vital role in cellular communication and response to external stimuli. This cyclic nucleotide is synthesized from ATP through the action of adenylate cyclase, which is activated by the binding of ligands to G protein-coupled receptors. The increase in cAMP concentration subsequently activates cAMP-dependent protein kinase, leading to the phosphorylation of target proteins and modulation of diverse cellular activities. Notably, cAMP is integral in mediating the effects of several hormones, including adrenocorticotropic hormone (ACTH), glucagon, and epinephrine, thereby influencing processes such as calcium transport, gene expression, and physiological responses related to growth, differentiation, and neurotransmission. Furthermore, the regulation of cAMP levels is tightly controlled by phosphodiesterases, which degrade cAMP, ensuring that signaling effects are appropriately timed and localized. Anti-cAMP antibody (9H4C4) is an essential tool for researchers investigating the intricate roles of cAMP in cellular signaling and its implications in various physiological and pathological conditions.

The preferred cAMP antibody is cAMP Antibody (AM01): sc-73761.