Molecular structure of Brodifacoum, CAS Number: 56073-10-0
Brodifacoum (CAS 56073-10-0)
Application:
Brodifacoum is a potent vitamin K antagonist anticoagulant agent
CAS Number:
56073-10-0
Molecular Weight:
523.42
Molecular Formula:
C31H23BrO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Brodifacoum is a chemical that functions as an anticoagulant by inhibiting the enzyme vitamin K epoxide reductase. This inhibition prevents the recycling of vitamin K, which is necessary for the production of clotting factors in the liver. As a result, brodifacoum disrupts the blood clotting process, leading to hemorrhage and ultimately death in target organisms. At the molecular level, brodifacoum interferes with the normal function of vitamin K, causing a depletion of active clotting factors and an inability to form blood clots. This mechanism of action makes brodifacoum an effective tool for controlling rodent populations and other pests in experimental applications.
Brodifacoum (CAS 56073-10-0) References
- Effects of Low-level Brodifacoum Exposure on the Feline Immune Response. | Kopanke, JH., et al. 2018. Sci Rep. 8: 8168. PMID: 29802369
- The relative toxicity of brodifacoum enantiomers. | Feinstein, DL., et al. 2019. Toxicol Lett. 306: 61-65. PMID: 30779948
- Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells. | Sachdev, S., et al. 2019. PeerJ. 7: e7733. PMID: 31579608
- Effects of brodifacoum and diphacinone exposure on four species of reptiles: tissue residue levels and survivorship. | Mauldin, RE., et al. 2020. Pest Manag Sci. 76: 1958-1966. PMID: 31858711
- Brodifacoum Poisoning Linked to Synthetic Marijuana Use in Wisconsin. | Kircher, M. and Perez, J. 2020. WMJ. 119: 129-131. PMID: 32659068
- Sudden nasal bleeding and brodifacoum: A case of accidental exposure or attempted homicide? | Foti, F., et al. 2020. Leg Med (Tokyo). 47: 101772. PMID: 32771937
- Brodifacoum-Laced Synthetic Marijuana Toxicity: A Fight Against Time. | Kumar, S. and Bhagia, G. 2020. Am J Case Rep. 21: e927111. PMID: 33132381
- Exposure of passerine birds to brodifacoum during management of Norway rats on farms. | Walther, B., et al. 2021. Sci Total Environ. 762: 144160. PMID: 33373750
- Brodifacoum pharmacokinetics in acute human poisoning: implications for estimating duration of vitamin K therapy. | Nosal, DG., et al. 2021. Toxicol Commun. 5: 69-72. PMID: 33768191
- The effects of brodifacoum cereal bait pellets on early life stages of the rice coral Montipora capitata. | Barkman, AL. and Richmond, RH. 2022. PeerJ. 10: e13877. PMID: 35990912
- Brodifacoum Levels and Biomarkers in Coastal Fish Species following a Rodent Eradication in an Italian Marine Protected Area: Preliminary Results. | Caliani, I., et al. 2023. Life (Basel). 13: PMID: 36836772
- Dispositional and pharmacodynamic characteristics of brodifacoum in warfarin-sensitive rats. | Bachmann, KA. and Sullivan, TJ. 1983. Pharmacology. 27: 281-8. PMID: 6657737
- Symptomatic brodifacoum ingestion requiring high-dose phytonadione therapy. | Sheen, SR., et al. 1994. Vet Hum Toxicol. 36: 216-7. PMID: 8066968
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Brodifacoum, 100 mg | sc-239414 | 100 mg | $131.00 |