Date published: 2026-9-5

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BAY U6751 (CAS 114290-51-6)

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Alternate Names:
Bay W1807
CAS Number:
114290-51-6
Purity:
≥95%
Molecular Weight:
451.81
Molecular Formula:
C20H20ClNNa2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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In the context of biochemical and pharmacological research, BAY U6751 hydrate may be utilized as a tool compound to elucidate the functioning of specific cellular pathways or to better understand the molecular basis of certain physiological responses. The application of compounds like BAY U6751 hydrate can extend to the study of signal transduction mechanisms, where they may serve as agonists or antagonists of particular receptors or enzymes. This can provide valuable insights into the modulation of cellular signals, contributing to the foundational knowledge necessary for the development of novel strategies in biotechnology, material science, or even in the synthesis of new compounds with desired biological activities. Furthermore, BAY U6751 hydrate′s role in research may involve its use in in vitro (test tube) models to assess the impact of modulating specific biochemical pathways on cellular functions.


BAY U6751 (CAS 114290-51-6) References

  1. Diverse effects of two allosteric inhibitors on the phosphorylation state of glycogen phosphorylase in hepatocytes.  |  Latsis, T., et al. 2002. Biochem J. 368: 309-16. PMID: 12186629
  2. Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors.  |  Gregus, Z. and Németi, B. 2007. Toxicol Sci. 100: 44-53. PMID: 17693424
  3. Structure-activity relationships of flavonoids as potential inhibitors of glycogen phosphorylase.  |  Kato, A., et al. 2008. J Agric Food Chem. 56: 4469-73. PMID: 18494482
  4. The effect of glycogen phosphorolysis on basal glutaminergic transmission.  |  Mozrzymas, J., et al. 2011. Biochem Biophys Res Commun. 404: 652-5. PMID: 21146500
  5. Neuron-astrocyte interaction enhance GABAergic synaptic transmission in a manner dependent on key metabolic enzymes.  |  Kaczor, P., et al. 2015. Front Cell Neurosci. 9: 120. PMID: 25914620
  6. Involvement of cellular metabolism in age-related LTP modifications in rat hippocampal slices.  |  Drulis-Fajdasz, D., et al. 2015. Oncotarget. 6: 14065-81. PMID: 26101857
  7. Energy Metabolism of the Brain, Including the Cooperation between Astrocytes and Neurons, Especially in the Context of Glycogen Metabolism.  |  Falkowska, A., et al. 2015. Int J Mol Sci. 16: 25959-81. PMID: 26528968
  8. Key Metabolic Enzymes Underlying Astrocytic Upregulation of GABAergic Plasticity.  |  Kaczor, PT. and Mozrzymas, JW. 2017. Front Cell Neurosci. 11: 144. PMID: 28559800
  9. Glycogenolysis in Cerebral Cortex During Sensory Stimulation, Acute Hypoglycemia, and Exercise: Impact on Astrocytic Energetics, Aerobic Glycolysis, and Astrocyte-Neuron Interactions.  |  Dienel, GA. and Rothman, DL. 2019. Adv Neurobiol. 23: 209-267. PMID: 31667811
  10. Validated liquid chromatography-mass spectrometry method for the quantification of glycogenolysis phosphorylase inhibitor in mouse tissues - 5-isopropyl-4-(2-chlorophenyl)-1-ethyl-1,4-dihydro-6-methyl-2,3,5-pyridinetricarboxylic acid ester disodium salt hydrate.  |  Pudelko-Malik, N., et al. 2022. J Sep Sci. 45: 3791-3799. PMID: 35964279

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

BAY U6751, 5 mg

sc-257117
5 mg
$265.00

BAY U6751, 50 mg

sc-257117A
50 mg
$1428.00