Apoptotic Myeloid Marker Antibody (BOB78): sc-130293
- Apoptotic Myeloid Marker Antibody (BOB78) is a mouse monoclonal mouse IgM κ κ provided at 200 µg/ml
- raised against apoptotic THP-1 cells of human origin
- recommended for detection of the surface marker of all late stage apoptotic myeloid cells of human origin by IP, IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Apoptotic Myeloid Marker Antibody (BOB78). This work is in progress.
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Apoptotic Myeloid Marker Antibody (BOB78) is a mouse monoclonal IgM antibody that detects Apoptotic Myeloid Marker in human samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Apoptotic Myeloid Marker (BOB78) antibody plays a crucial role in identifying myeloid cells undergoing apoptosis, which is essential for understanding various physiological and pathological processes, including immune responses and tissue homeostasis. Apoptotic Myeloid Marker is primarily located in the cytoplasm of myeloid cells, where Apoptotic Myeloid Marker participates in the regulation of apoptosis, a vital process that ensures the removal of damaged or unnecessary cells. This regulation is particularly important in the context of diseases such as cancer and autoimmune disorders, where dysregulation of apoptosis can lead to the survival of harmful cells. Anti-Apoptotic Myeloid Marker antibody (BOB78) enables researchers to gain insights into the mechanisms of myeloid cell apoptosis, contributing to the development of targeted therapies and improving our understanding of immune system dynamics.
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Apoptotic Myeloid Marker Antibody (BOB78) References:
- Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype. | Horckmans, M., et al. 2017. Eur Heart J. 38: 187-197. PMID: 28158426
- Latest perspectives on macrophages in bone homeostasis. | Bozec, A. and Soulat, D. 2017. Pflugers Arch. 469: 517-525. PMID: 28247013
- Apoptotic Cell-Directed Resolution of Lung Inflammation Requires Myeloid αv Integrin-Mediated Induction of Regulatory T Lymphocytes. | Zhang, A., et al. 2020. Am J Pathol. 190: 1224-1235. PMID: 32201264
- Deletion of TLR4 attenuates lipopolysaccharide-induced acute liver injury by inhibiting inflammation and apoptosis. | Chen, SN., et al. 2021. Acta Pharmacol Sin. 42: 1610-1619. PMID: 33495514
- The potential of proliferative and apoptotic parameters in clinical flow cytometry of myeloid malignancies. | Mestrum, SGC., et al. 2021. Blood Adv. 5: 2040-2052. PMID: 33847740
- Acute myeloid leukemia: therapeutic targeting of stem cells. | Pabon, CM., et al. 2022. Expert Opin Ther Targets. 26: 547-556. PMID: 35634856
- Old plasma dilution reduces human biological age: a clinical study. | Kim, D., et al. 2022. Geroscience. 44: 2701-2720. PMID: 35999337
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush. | Zaidi, SAH., et al. 2023. Cell Death Dis. 14: 661. PMID: 37816735
- Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide. | Cristaldi, M., et al. 2023. Cell Death Dis. 14: 773. PMID: 38007509
- Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. | Dawson, A., et al. 2024. Nat Commun. 15: 1090. PMID: 38316788
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Apoptotic Myeloid Marker Antibody (BOB78) | sc-130293 | 200 µg/ml | $322.00 | |||
Apoptotic Myeloid Marker Antibody (BOB78): m-IgGκ BP-HRP Bundle | sc-551864 | 200 µg Ab; 40 µg BP | $361.00 | |||
Apoptotic Myeloid Marker Antibody (BOB78) FITC | sc-130293 FITC | 200 µg/ml | $336.00 | |||
Apoptotic Myeloid Marker Antibody (BOB78) PE | sc-130293 PE | 200 µg/ml | $349.00 |