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Aldicarb (CAS 116-06-3)

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Alternate Names:
O-(Methylcarbamoyl)-2-methyl-2-(methylthio)propionaldehyd-oxime
Application:
Aldicarb is A cholinesterase inhibitor which prevents the breakdown of ACh in the synapse
CAS Number:
116-06-3
Purity:
≥98%
Molecular Weight:
190.26
Molecular Formula:
C7H14N2O2S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Aldicarb is a inhibitor of BChE and AChE (cholinesterase) which prevents the breakdown of ACh in the synapse. Aldicarb has historically been utilized as a pesticide. It is absorbed by plants and can act on pests that ingest the plant material. It is also highly soluble in water, which facilitates its application and movement within the soil and plants. In non-agricultural contexts, aldicarb can be studied for its chemical behavior and interactions in various environments. Research may focus on its degradation pathways, the persistence of its metabolites in soil and water, and its impact on non-target organisms.


Aldicarb (CAS 116-06-3) References

  1. Determination of aldicarb, aldicarb sulfoxide and aldicarb sulfone in some fruits and vegetables using high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.  |  Nunes, GS., et al. 2000. J Chromatogr A. 888: 113-20. PMID: 10949478
  2. Aldicarb and carbofuran transport in a Hapludalf influenced by differential antecedent soil water content and irrigation delay.  |  Kazemi, HV., et al. 2009. Chemosphere. 74: 265-73. PMID: 18926555
  3. Accelerated degradation of aldicarb and its metabolites in cotton field soils.  |  Lawrence, KS., et al. 2005. J Nematol. 37: 190-7. PMID: 19262860
  4. Effects of aldicarb and its sulfoxide and sulfone on the biology of Tylenchulus semipenetrans.  |  Huang, SP. and Van Gundy, SD. 1978. J Nematol. 10: 100-6. PMID: 19305820
  5. Aldicarb treatment inhibits the stimulatory activity of macrophages without affecting the T-cell responses in the syngeneic mixed lymphocyte reaction.  |  Dean, TN., et al. 1990. Int J Immunopharmacol. 12: 337-48. PMID: 2139433
  6. Aldicarb-induced Paralysis Assay to Determine Defects in Synaptic Transmission in Caenorhabditis elegans.  |  Oh, KH. and Kim, H. 2017. Bio Protoc. 7: PMID: 28868330
  7. Organoleptic assessment and median lethal dose determination of oral aldicarb in rats.  |  Rice, NC., et al. 2020. Ann N Y Acad Sci. 1480: 136-145. PMID: 32761625
  8. Interaction of Human Alpha-2-Macroglobulin with Pesticide Aldicarb Using Spectroscopy and Molecular Docking.  |  Dixit, S., et al. 2021. Protein Pept Lett. 28: 315-322. PMID: 32957873
  9. The toxicologic effects of the carbamate insecticide aldicarb in mammals: a review.  |  Risher, JF., et al. 1987. Environ Health Perspect. 72: 267-81. PMID: 3304999
  10. Determination of Aldicarb, Carbofuran and Methamidophos in Blood Derived from Forensic Cases through Liquid Chromatography with Electrospray Ionization and Tandem Mass Spectrometry (LC--ESI-MS-MS).  |  Mariño, D. and Patiño, N. 2022. J Anal Toxicol. 46: 37-46. PMID: 33258956
  11. Atropine reduces aldicarb-induced sensitivity to C. elegans electroshock model.  |  Suthakaran, N., et al. 2022. MicroPubl Biol. 2022: PMID: 36017190
  12. Hapten designs based on aldicarb for the development of a colloidal gold immunochromatographic quantitative test strip.  |  Shen, H., et al. 2022. Front Nutr. 9: 976284. PMID: 36082035
  13. Aldicarb poisoning. A case report with prolonged cholinesterase inhibition and improvement after pralidoxime therapy.  |  Burgess, JL., et al. 1994. Arch Intern Med. 154: 221-4. PMID: 8285817

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Aldicarb, 100 mg

sc-254939
100 mg
$100.00