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3-Methyl-5-AIQ hydrochloride MF: C10H10N2O•HCl
MW: 210.6
A PARP-1inhibitor that arrests apoptosis by PARP.
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  3. Protein-Interacting Inhibitors, Activators & Substrates
  4. Protein Inhibidores
  5. PARP Inhibidores
  6. 3-Methyl-5-AIQ hydrochloride

3-Methyl-5-AIQ hydrochloride

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Solicitud: 3-Methyl-5-AIQ hydrochloride is a PARP-1inhibitor that arrests apoptosis by PARP
Pureza: ≥98%
Peso Molecular: 210.6
Fórmula Molecular: C10H10N2O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

ENLACES RÁPIDOS

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3-Methyl-5-AIQ hydrochloride is a strong inhibitor of poly(ADP-ribose) polymerase-1 in vitro. Exhibits outstanding therapeutic benefits in models of myocardial infarction, ischaemia-reperfusion of the liver and kidney, heart transplantation and acute lung inflammation.


References

Synthesis and PARP-1 inhibitory activity of 3-substituted analogues of the potent water-soluble PARP inihbitor 5-aminoisoquinolin-1-one (5-AIQ): E. C. Y. Woon, et al.; Bioorg. Med. Chem. (submitted), (2006)

Estado de Materia :
Solid
Solubilidad :
Soluble in water or DMSO
ALMACENAMIENTO :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
57370059
SMILES :
Cl.CC1=CC2=C(C=CC=C2N)C(=O)N1

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CERTIFICADO DE ANÁLISIS

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